{"id":"W4414170107","doi":"10.1186/s13765-025-01026-5","title":"Protective effects of Dioscorea bulbifera and Zingiber officinale mixed extracts against glutamate-induced cell death in HT22 cells","year":2025,"lang":"en","type":"article","venue":"Applied Biological Chemistry","topic":"Medicinal Plants and Neuroprotection","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Aging","funders":"Ministry of Education, Science and Technology; National Research Foundation of Korea; Korea Institute of Oriental Medicine; National Research Foundation; National Center of Competence in Research AntiResist","keywords":"Neuroprotection; Oxidative stress; Reactive oxygen species; Excitotoxicity; Programmed cell death; Antioxidant; Neurotoxicity; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001647818,0.0002176334,0.0004674063,0.00005163478,0.00004069431,0.00000655968,0.00007465394,0.0003047327,0.0000149701],"category_scores_gemma":[0.0001362318,0.0001512184,0.00004812924,0.0001599619,0.00008030349,0.00001231016,0.00006486342,0.0004748746,0.000003326388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004671068,"about_ca_system_score_gemma":0.000050393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002400784,"about_ca_topic_score_gemma":7.677477e-7,"domain_scores_codex":[0.9988468,0.0000282007,0.0003037543,0.0004365908,0.0001314386,0.0002531902],"domain_scores_gemma":[0.9993362,0.0002265376,0.0001121865,0.0001875214,0.000033665,0.0001038243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006795794,0.0003085814,0.0009154209,0.001152943,0.00001877332,0.00008670735,0.00003030687,0.000002046889,0.9935315,0.00003273786,0.00001488683,0.003226518],"study_design_scores_gemma":[0.001788819,0.0002430094,0.03677994,0.0003195549,0.00003704237,0.00001291618,0.00005335935,0.00003794277,0.9604038,0.000122324,0.00007325798,0.0001280131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867349,0.0001173905,0.00006793842,0.00004895905,0.00005343828,0.0009388856,0.000003706334,0.00004458884,0.01199023],"genre_scores_gemma":[0.9993115,0.00007735401,0.0001118185,0.0002086865,0.00005014257,0.00009808821,0.00001593276,0.000009599579,0.00011685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03586452,"threshold_uncertainty_score":0.6166508,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01356280092071796,"score_gpt":0.2334299230899968,"score_spread":0.2198671221692788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}