{"id":"W4414195801","doi":"10.1007/s40883-025-00473-2","title":"Safety and Biocompatibility of a Spray-Dried Influenza Microparticle Vaccine in Mice","year":2025,"lang":"en","type":"article","venue":"Regenerative Engineering and Translational Medicine","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institute of Allergy and Infectious Diseases; Nanovaccine Institute, Iowa State University; National Institutes of Health; Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; Iowa State University","keywords":"Biocompatibility; Microparticle; Influenza vaccine; Immunogenicity; Immune system; Vaccination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004543512,0.0003281425,0.000216941,0.000315442,0.000112272,0.0002108925,0.0002303101,0.0005193831,0.0009039032],"category_scores_gemma":[0.0002566634,0.0001274188,0.0003596425,0.0001057579,0.000206342,0.0002935494,0.0001066559,0.0004734191,0.0003172304],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002024214,"about_ca_system_score_gemma":0.0001537897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004669985,"about_ca_topic_score_gemma":0.0003586416,"domain_scores_codex":[0.999769,0.00003551473,0.00001789382,0.00005915209,0.00008743322,0.00003089885],"domain_scores_gemma":[0.9997476,0.00003875091,0.0001065544,0.00003037158,0.00005139529,0.0000254284],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000416106,0.0000948395,0.0003117465,0.00003848647,0.000009917,0.00002219084,0.00001606647,0.00010722,0.9964636,0.00002232632,0.00004234137,0.002455233],"study_design_scores_gemma":[0.00002442913,0.003424847,0.003487889,0.000008288414,0.00003338234,0.00009203634,0.00001056985,0.0006057189,0.9914266,0.00001848717,0.0008620742,0.000005754658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992706,0.001598584,0.00409007,0.00007529727,0.0000538664,0.00009186353,0.0005712957,0.00009446142,0.0007185159],"genre_scores_gemma":[0.9921795,0.0008392032,0.003851611,0.00007166751,0.00002143251,0.000116424,0.0005901909,0.0000273155,0.002302759],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009039032,"threshold_uncertainty_score":0.003023863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0346339995442978,"score_gpt":0.3420670906317748,"score_spread":0.307433091087477,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}