{"id":"W4414240310","doi":"10.51731/cjht.2025.1223","title":"Abemaciclib (Verzenio)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Fulvestrant; Metastatic breast cancer; Breast cancer; Crizotinib; Cancer; Population; Drug; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002004277,0.0005503548,0.0006291752,0.001063681,0.0004702214,0.0009109083,0.000746029,0.0007244187,0.0487765],"category_scores_gemma":[0.0004021533,0.0002362806,0.000445568,0.0005603619,0.0003495545,0.0005416134,0.0005164982,0.001929928,0.01729652],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001030513,"about_ca_system_score_gemma":0.001510148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005933949,"about_ca_topic_score_gemma":0.0122367,"domain_scores_codex":[0.9997886,0.00002235167,0.00001371457,0.00004524753,0.00008065967,0.00004946754],"domain_scores_gemma":[0.9998775,0.00001068742,0.00001771694,0.00001278442,0.00002743677,0.00005391722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005287947,0.001500635,0.0008209741,0.001942003,0.0001283239,0.0009568867,0.00007839832,0.0005687329,0.0665039,0.005731577,0.1710571,0.7454236],"study_design_scores_gemma":[0.004898226,0.002801007,0.004454725,0.0004606748,0.0001535789,0.00434326,0.00005312503,0.0008296972,0.03202822,0.001556626,0.9483595,0.00006133605],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.1228729,0.1528527,0.00843899,0.009774781,0.004379301,0.002573162,0.01438634,0.00763072,0.677091],"genre_scores_gemma":[0.5582665,0.07817325,0.01084842,0.01164291,0.0009063791,0.001019262,0.02609225,0.0007039084,0.3123472],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.0487765,"threshold_uncertainty_score":0.1631737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0164966476193435,"score_gpt":0.3269568899253435,"score_spread":0.310460242306,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}