{"id":"W4414279821","doi":"10.1681/asn.0000000838","title":"Authors' Reply: Tirzepatide and Kidney Protection in Obesity: Unanswered Questions","year":2025,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"","keywords":"Overweight; Semaglutide; Clinical trial; Population; Type 2 diabetes; Diabetes mellitus; Kidney disease; Biomarker","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008839151,0.001068369,0.002627051,0.001009515,0.002972642,0.003346911,0.003493861,0.03833726,0.007477519],"category_scores_gemma":[0.05073505,0.0008692958,0.001919147,0.000803639,0.004431661,0.006524153,0.002442784,0.0515787,0.006057318],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001935948,"about_ca_system_score_gemma":0.003895516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00211369,"about_ca_topic_score_gemma":0.001910057,"domain_scores_codex":[0.9964095,0.001184709,0.0005835834,0.0005504844,0.0009315299,0.0003403104],"domain_scores_gemma":[0.9722153,0.01650868,0.001730569,0.0008372067,0.006838128,0.001870076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001072477,0.00003229174,0.0004402704,0.0001623623,0.00003928771,0.000554184,0.0001486564,0.00005162933,0.0001092872,0.001154122,0.9881361,0.009064532],"study_design_scores_gemma":[0.0002548611,0.0001681483,0.001291665,0.0006146946,0.0001037583,0.002994595,0.0007330573,0.0004222863,0.0005240293,0.007759533,0.9849358,0.0001975723],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002334004,0.003360276,0.0001239965,0.9513232,0.0445372,0.000009566995,0.00006173468,0.00005180947,0.0002987993],"genre_scores_gemma":[0.002312445,0.002497999,0.000301908,0.9274973,0.06595169,0.00003842057,0.0000319908,0.00003025211,0.001338056],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03833726,"threshold_uncertainty_score":0.04674643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01132505059277258,"score_gpt":0.2751757220232381,"score_spread":0.2638506714304655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}