{"id":"W4414283050","doi":"10.51731/cjht.2025.1225","title":"Amivantamab (Rybrevant)","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Exon; Lung cancer; Pemetrexed; Carboplatin; Drug; Disease; Mutation; Epidermal growth factor receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002983576,0.000374416,0.0004809365,0.0005822931,0.0003218373,0.0006712736,0.0005137405,0.0008765123,0.02186195],"category_scores_gemma":[0.000434423,0.0001558153,0.0005132068,0.0003361624,0.000218717,0.0003981341,0.0004315651,0.001797602,0.01112065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009022863,"about_ca_system_score_gemma":0.0007961243,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003983028,"about_ca_topic_score_gemma":0.006871759,"domain_scores_codex":[0.9997999,0.00002734745,0.0000130913,0.00003899636,0.00007439417,0.00004625318],"domain_scores_gemma":[0.9998779,0.00001311794,0.0000232062,0.000009229731,0.00002424953,0.00005229183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003510095,0.0007768297,0.002112028,0.001083042,0.0002091281,0.001565811,0.00007607209,0.0006049794,0.04554396,0.004921845,0.1208916,0.8187047],"study_design_scores_gemma":[0.005192002,0.003689457,0.008915256,0.0003957972,0.0001782059,0.009002926,0.00004184246,0.0008861247,0.02048403,0.001269804,0.949888,0.00005647146],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.1892256,0.3317383,0.007129994,0.01913239,0.004258058,0.001590817,0.009343537,0.004460432,0.433121],"genre_scores_gemma":[0.6658065,0.07717381,0.006803318,0.01224514,0.001126181,0.0006993143,0.01744751,0.0002397155,0.2184586],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.996017,"threshold_uncertainty_score":0.0731355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01448935083295981,"score_gpt":0.3545799191784978,"score_spread":0.340090568345538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}