{"id":"W4414287385","doi":"10.14740/wjon2529","title":"Invasive Lobular Carcinoma Has Higher Immune Response Than Invasive Ductal Carcinoma in Estrogen Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Breast Cancers","year":2025,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; U.S. Department of Defense","keywords":"Immune system; Estrogen receptor; Invasive lobular carcinoma; Infiltration (HVAC); Epidermal growth factor receptor; Estrogen; Epidermal growth factor; Invasive ductal carcinoma; Breast cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003008185,0.0002042337,0.0003519621,0.0008992716,0.0003502145,0.0006367848,0.0001838077,0.0002609282,0.004796373],"category_scores_gemma":[0.0006240776,0.00009423446,0.000352951,0.0007134522,0.0001886682,0.0002110265,0.0003853374,0.000302321,0.0004353242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002788164,"about_ca_system_score_gemma":0.0002225211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001187806,"about_ca_topic_score_gemma":0.002249739,"domain_scores_codex":[0.9998017,0.00002705886,0.00002194434,0.00006334582,0.00004075193,0.00004526439],"domain_scores_gemma":[0.9994505,0.00008469114,0.0002349659,0.00005215331,0.00006203249,0.0001156192],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002965898,0.00002360881,0.991344,0.00003908705,0.00007877547,0.0001217763,0.00004921822,0.00003661294,0.004974447,0.00004167856,0.0001660537,0.002828341],"study_design_scores_gemma":[0.000004842384,0.00003956196,0.9981634,0.000004812757,0.00004865155,0.0005361428,0.00009794097,0.00007277613,0.000528675,0.00005132379,0.0004495285,0.000002276551],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976164,0.0005606373,0.0001714607,0.0000436124,0.000008754079,0.00000805005,0.0004196962,0.00001438822,0.001156874],"genre_scores_gemma":[0.9986891,0.0001064603,0.0001394696,0.00005212084,0.00001254374,0.00001186419,0.0005811049,0.000007412992,0.0003998983],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004796373,"threshold_uncertainty_score":0.01604551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01633303187733198,"score_gpt":0.2736894980751617,"score_spread":0.2573564661978298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}