{"id":"W4414295928","doi":"10.1021/envhealth.5c00227","title":"Malignant Transformation of Human Uroepithelial Cells Induced by Long-Term Exposure to a Disinfection Byproduct─2,6-Dichlorobenzoquinone","year":2025,"lang":"en","type":"article","venue":"Environment & Health","topic":"Chemical Analysis and Environmental Impact","field":"Environmental Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Innovates; China Scholarship Council; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Vinculin; Malignant transformation; Extracellular matrix; Cytoskeleton; Actin; Cell culture; Extracellular; Immunofluorescence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007771643,0.0002361401,0.000158923,0.0002385392,0.0001913007,0.0002566678,0.0000804555,0.0001798887,0.0006309986],"category_scores_gemma":[0.0000829305,0.0001033391,0.0002737326,0.0002424519,0.0001392478,0.0001464936,0.0002263088,0.0001757246,0.0001768139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001416732,"about_ca_system_score_gemma":0.0001316264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009567641,"about_ca_topic_score_gemma":0.00116754,"domain_scores_codex":[0.9998963,0.00001251512,0.00001012974,0.00002458159,0.00003111146,0.00002535053],"domain_scores_gemma":[0.9999338,0.000009915329,0.00001870192,0.000009742634,0.00001707432,0.00001075133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003601188,0.00001034719,0.001191132,0.00002420434,0.000005158063,0.00005241392,0.0000262058,0.00001522762,0.9978149,0.00001020925,0.00001089023,0.0008033131],"study_design_scores_gemma":[0.000003577091,0.000339296,0.08436032,0.000007087309,0.00002777574,0.0004187543,0.0001609625,0.0003716979,0.9123982,0.00003209618,0.001874303,0.000005931283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965211,0.001800598,0.0009098586,0.00003237767,0.000009964139,0.00001058795,0.0002804913,0.00001543415,0.0004195874],"genre_scores_gemma":[0.9956125,0.00158739,0.0009171617,0.00003379505,0.000006447517,0.00001885868,0.0007351042,0.000004699566,0.001084094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009567641,"threshold_uncertainty_score":0.002110898,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009464515839935453,"score_gpt":0.2544026104829064,"score_spread":0.2449380946429709,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}