{"id":"W4414317048","doi":"10.1111/cpr.70131","title":"Targeting the Secretin Receptor in Macrophages Attenuates Silica‐Induced Pulmonary Fibrosis","year":2025,"lang":"en","type":"letter","venue":"Cell Proliferation","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Science Foundation of Hebei Province; National Natural Science Foundation of China","keywords":"Macrophage; Pulmonary fibrosis; Lung; Receptor; Secretin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003481368,0.0004712611,0.000568342,0.0002503588,0.0002352476,0.0001231175,0.0002724663,0.000840702,0.0003736098],"category_scores_gemma":[0.0001568763,0.0003556805,0.0002887804,0.0003575547,0.0000775952,0.000126916,0.0001197427,0.00194585,0.0001397854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002611993,"about_ca_system_score_gemma":0.0003283791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001103683,"about_ca_topic_score_gemma":0.000001933158,"domain_scores_codex":[0.9972734,0.0003275117,0.000684983,0.0007106625,0.0004766329,0.0005267746],"domain_scores_gemma":[0.9987693,0.000198248,0.000239892,0.0005203014,0.0001982643,0.0000740142],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008731436,0.0001180836,0.0008751252,0.001887635,0.00004008705,0.0002366098,0.0002001734,0.00001471257,0.07051741,0.000005251065,0.9246073,0.0006244957],"study_design_scores_gemma":[0.002128243,0.002975595,0.001276453,0.006465124,0.001146278,0.00007770625,0.0006224904,0.01437053,0.06729368,0.0003519805,0.901255,0.002036969],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.0616877,0.004281261,0.00007976177,0.9187826,0.001808819,0.004158197,0.0003328248,0.0002462872,0.008622587],"genre_scores_gemma":[0.571862,0.0005044568,0.0002662133,0.377997,0.01169419,0.0007584547,0.007942528,0.0001497874,0.02882543],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.5407856,"threshold_uncertainty_score":0.9998895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016324353726677,"score_gpt":0.2406875611567718,"score_spread":0.2305243176195051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}