{"id":"W4414335364","doi":"10.1007/s11248-025-00462-9","title":"Transgenic inducible MHC I overexpression in mouse alveolar type 2 cells","year":2025,"lang":"en","type":"article","venue":"Transgenic Research","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Major histocompatibility complex; MHC class I; CD8; Downregulation and upregulation; Genetically modified mouse; Transgene; MHC class II; Lung","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005080427,0.0005397121,0.0002672014,0.0005764392,0.0003381884,0.0005669378,0.0005444402,0.0004858192,0.002936688],"category_scores_gemma":[0.0001871243,0.0003096381,0.0004732948,0.0004358962,0.000359653,0.0003409451,0.000292528,0.001468322,0.001335732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000373829,"about_ca_system_score_gemma":0.0003766321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000794858,"about_ca_topic_score_gemma":0.001110894,"domain_scores_codex":[0.9994714,0.00007539276,0.00006724636,0.0001144933,0.0001371805,0.0001344699],"domain_scores_gemma":[0.9996481,0.00006643069,0.00008979024,0.00005614339,0.00004351639,0.00009608029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009838734,0.00003716938,0.00007910148,0.00001635931,0.000003680509,0.00004464901,0.0000194222,0.00004986855,0.9988214,0.0002645625,0.00007754984,0.0004878015],"study_design_scores_gemma":[0.00004638172,0.0001552365,0.0009468325,0.000006996305,0.00002012007,0.0001957188,0.00005000036,0.0008767649,0.9930513,0.00006303212,0.004582919,0.000004630754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9467365,0.001377055,0.0358279,0.0005609969,0.0005567612,0.0003830224,0.005300949,0.0007658377,0.008491051],"genre_scores_gemma":[0.9563969,0.000999956,0.01827517,0.0001908589,0.00009561897,0.0003528434,0.003830324,0.0002489378,0.01960938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002936688,"threshold_uncertainty_score":0.009824216,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1652314913640534,"score_gpt":0.4878913025654292,"score_spread":0.3226598112013758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}