{"id":"W4414347771","doi":"10.1093/nutrit/nuaf172","title":"Berberine: A Bitter Phytochemical With Diversely Sweet Therapeutic Properties","year":2025,"lang":"en","type":"article","venue":"Nutrition Reviews","topic":"Berberine and alkaloids research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Science Centre for Human and Animal Health; Agriculture and Agri-Food Canada; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Berberine; Phytochemical; In vivo; Type 2 diabetes; Diabetes mellitus; Antioxidant; Insulin; Phytotherapy; Biological activity","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002007825,0.0004618017,0.0005997099,0.001363212,0.0003603007,0.0006994495,0.0002176287,0.0006390285,0.002460962],"category_scores_gemma":[0.0002090118,0.0001360475,0.0002526319,0.0006810565,0.0002711642,0.0009089329,0.000462135,0.0007292281,0.0008704056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002408625,"about_ca_system_score_gemma":0.0002048924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002620771,"about_ca_topic_score_gemma":0.0005650677,"domain_scores_codex":[0.9998666,0.00002885063,0.00001875587,0.0000328068,0.00003613562,0.00001690009],"domain_scores_gemma":[0.999918,0.00002571486,0.00002239812,0.000003958147,0.00001839198,0.00001151119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007241251,0.0002710045,0.001740338,0.01414902,0.0001423501,0.001868832,0.0005143707,0.0003807365,0.2408546,0.006861767,0.01085666,0.7216362],"study_design_scores_gemma":[0.00007172171,0.0009003489,0.01290369,0.001901252,0.0002709303,0.01232397,0.0002290033,0.0003080431,0.07828763,0.003064427,0.8896229,0.0001161001],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01833019,0.9704843,0.002073501,0.001185592,0.0003799729,0.00002859584,0.0001816783,0.00007960648,0.007256553],"genre_scores_gemma":[0.1484445,0.8275108,0.00691545,0.001857469,0.0008292375,0.00004448547,0.0004364272,0.0000598654,0.01390184],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002460962,"threshold_uncertainty_score":0.008232713,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05382231778578426,"score_gpt":0.3280309995009911,"score_spread":0.2742086817152068,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}