{"id":"W4414352545","doi":"10.3390/cancers17183068","title":"Future Directions and Priorities for Cellular Therapy in Sarcoma: A Report from the Strategic Advances in Sarcoma Science Cell Therapy Breakout","year":2025,"lang":"en","type":"review","venue":"Cancers","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; National Institutes of Health","keywords":"Cell therapy; Synovial sarcoma; Sarcoma; Cell; Cancer therapy; Tumor microenvironment; Breakout","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002317413,0.000957767,0.001055626,0.002173619,0.0003872215,0.002098461,0.0007537341,0.002164514,0.004356068],"category_scores_gemma":[0.001957801,0.0003481645,0.000792881,0.002177415,0.0006611922,0.003574377,0.001291215,0.004377733,0.002448596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001544681,"about_ca_system_score_gemma":0.003790908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001732288,"about_ca_topic_score_gemma":0.002756631,"domain_scores_codex":[0.999575,0.00007391012,0.00005494168,0.00006675045,0.0001703169,0.00005920466],"domain_scores_gemma":[0.9986614,0.0006380466,0.0001127347,0.00002951862,0.0004116805,0.0001465837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001443724,0.00008386683,0.0001519835,0.01157067,0.00006238889,0.0001918183,0.0001041093,0.0004507831,0.001455876,0.01278269,0.1397636,0.8332379],"study_design_scores_gemma":[0.00002195969,0.00008355686,0.0002931633,0.003692428,0.00005863254,0.0003297821,0.00007153134,0.00007531806,0.0002175326,0.002056378,0.9930861,0.00001380206],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008143447,0.9952159,0.000132612,0.002437757,0.0009823518,0.000007913961,0.00002808091,0.000009945833,0.001103921],"genre_scores_gemma":[0.0006099992,0.9958535,0.0003545375,0.001729018,0.0005127309,0.00001183225,0.00005184686,0.000003477842,0.0008729073],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004356068,"threshold_uncertainty_score":0.01457244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05263259506102581,"score_gpt":0.3777831572277143,"score_spread":0.3251505621666885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}