{"id":"W4414379657","doi":"10.1093/molehr/gaaf047","title":"Permutation tests to assess sex differences in omics data","year":2025,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"B.C. Women's Hospital & Health Centre; BC Children's Hospital; Women's Health Research Institute; Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Spurious relationship; Permutation (music); Omics; False discovery rate; Statistical hypothesis testing; Resampling; Multiple comparisons problem","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03088572,0.001488391,0.001989823,0.004213607,0.001747878,0.002686787,0.002236366,0.001994154,0.01294967],"category_scores_gemma":[0.1564734,0.0008185858,0.003452265,0.003698691,0.00348194,0.002138757,0.002862258,0.005830763,0.001581136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00121465,"about_ca_system_score_gemma":0.002453245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001689556,"about_ca_topic_score_gemma":0.001658091,"domain_scores_codex":[0.9744892,0.01516664,0.002010789,0.004411101,0.003265637,0.0006566347],"domain_scores_gemma":[0.862446,0.1172467,0.005324108,0.01077664,0.003072426,0.00113419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.005381799,0.00138766,0.1967653,0.004839779,0.01427979,0.004084789,0.002768897,0.08540711,0.03059446,0.149215,0.05926585,0.4460096],"study_design_scores_gemma":[0.001162001,0.003530702,0.09822284,0.0008532921,0.002058524,0.002842562,0.001868051,0.4409119,0.02265343,0.3607341,0.06465299,0.0005095366],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1121255,0.001825071,0.8560634,0.001358532,0.001171419,0.002497202,0.009965904,0.008025229,0.006967797],"genre_scores_gemma":[0.4672917,0.0006820583,0.5069452,0.001801116,0.0003891586,0.007967233,0.01004949,0.00252452,0.00234953],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.03088572,"threshold_uncertainty_score":0.1633413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03808049547343004,"score_gpt":0.3123176409294104,"score_spread":0.2742371454559803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}