{"id":"W4414381536","doi":"10.1016/j.chom.2025.08.011","title":"Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication","year":2025,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Canadian Institutes of Health Research; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung","keywords":"Immune system; Flagellin; Commensalism; Bacteria; Host (biology); Function (biology); Gut flora; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002224753,0.0003577699,0.0002578375,0.0002306476,0.0001586854,0.0004213059,0.00008494176,0.0003441497,0.001219173],"category_scores_gemma":[0.0001129416,0.0001200308,0.0003143382,0.0001259138,0.0002529197,0.0003358209,0.0004424264,0.0005521907,0.0003487849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002625708,"about_ca_system_score_gemma":0.0001557107,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001741814,"about_ca_topic_score_gemma":0.0003905126,"domain_scores_codex":[0.9998375,0.0000364585,0.00001006589,0.00003168844,0.00003126441,0.00005309605],"domain_scores_gemma":[0.999835,0.00002121327,0.00005549735,0.00001455798,0.00002034207,0.00005330835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000104204,0.000006731778,0.0002679847,0.00002055342,0.000002549844,0.00002638873,0.000007062342,0.000009098294,0.9987193,0.00005073087,0.000009378461,0.0007761298],"study_design_scores_gemma":[0.00002057453,0.000558498,0.0153724,0.00001698423,0.00001831101,0.0002310881,0.00009223293,0.0003257187,0.9805533,0.0001419844,0.002661147,0.000007679092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9865953,0.005555769,0.005150637,0.0002819638,0.00008529641,0.00004475796,0.000308487,0.00008017298,0.001897659],"genre_scores_gemma":[0.991783,0.001741383,0.004116512,0.0001582632,0.00002314737,0.00003260879,0.000282724,0.00001651525,0.001845846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001219173,"threshold_uncertainty_score":0.004078567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008050685255940033,"score_gpt":0.2588054150301625,"score_spread":0.2507547297742224,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}