{"id":"W4414465152","doi":"10.1158/2326-6074.cimm25-a002","title":"Abstract A002: Comprehensive blood profiling for immunotherapy outcome prediction and longitudinal immune trajectory characterisation","year":2025,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Blood groups and transfusion","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Adjuvant; Immunotherapy; Immune system; Peripheral blood mononuclear cell; Antibody; Clinical trial; Adverse effect; Univariate","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001342934,0.000617301,0.0005373094,0.001123665,0.0002761432,0.001384127,0.0004951414,0.0006312035,0.006147134],"category_scores_gemma":[0.002875395,0.0002141267,0.0004634981,0.001012622,0.0001921058,0.00043623,0.0006359969,0.0009064781,0.0023239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002746955,"about_ca_system_score_gemma":0.0005737735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009596418,"about_ca_topic_score_gemma":0.001093977,"domain_scores_codex":[0.9994548,0.0001624058,0.00004150689,0.0001798077,0.0001180992,0.00004345374],"domain_scores_gemma":[0.9985921,0.000431431,0.0002456509,0.0002214322,0.0003355505,0.0001737907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007749053,0.001275294,0.4269748,0.0007012355,0.0007461823,0.0004508774,0.0002826782,0.02018106,0.1833957,0.0016776,0.03742839,0.3191371],"study_design_scores_gemma":[0.000561017,0.004579389,0.6082861,0.0002005064,0.0006312901,0.00234729,0.0002737631,0.2428116,0.0857707,0.006237897,0.04811836,0.0001819753],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8279117,0.002485488,0.1104522,0.001184756,0.0002600982,0.0005696997,0.04543635,0.004728441,0.006971295],"genre_scores_gemma":[0.9191565,0.0006199349,0.04161742,0.000424175,0.0002398779,0.0007021936,0.03357884,0.0002247525,0.003436353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006147134,"threshold_uncertainty_score":0.02056426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1002259728567415,"score_gpt":0.4103035915137163,"score_spread":0.3100776186569748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}