{"id":"W4414465321","doi":"10.1158/2326-6074.cimm25-ia06","title":"Abstract IA06: Lifestyle induced susceptibility of immune related adverse events","year":2025,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Nutrition, Genetics, and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Adverse effect; Immune system; Cancer; Microbiome; Immunotherapy; Immunity; Downregulation and upregulation; Immune Dysfunction","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007749628,0.0001419063,0.0002230015,0.0001903342,0.0001557134,0.000004369799,0.000437218,0.0003670108,0.0002396739],"category_scores_gemma":[0.0004633918,0.0001497175,0.0001528089,0.0003586451,0.0004781339,0.000005375615,0.0003016722,0.0003645409,0.00002237872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007591258,"about_ca_system_score_gemma":0.0007848538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000327105,"about_ca_topic_score_gemma":0.0001213637,"domain_scores_codex":[0.9981734,0.0002753728,0.0004572854,0.0004612941,0.000186773,0.0004459313],"domain_scores_gemma":[0.9983875,0.00005020277,0.00009401047,0.0007936334,0.0006010107,0.00007362491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007216927,0.0003152628,0.06347974,0.0001019167,0.0002322897,0.000002855028,0.00004966544,0.000009635097,0.9321061,0.0001026316,0.0009900867,0.001888091],"study_design_scores_gemma":[0.001801778,0.0002474615,0.5208818,0.00008116511,0.00001982597,0.000001405067,0.0003087059,0.00000322082,0.4724091,0.001028977,0.003082849,0.0001336689],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844117,0.01247279,0.000006905474,0.0003809705,0.0003961031,0.0003610157,0.00004986721,0.00001295094,0.001907771],"genre_scores_gemma":[0.9950336,0.002702037,0.00002852222,0.00004023786,0.0000635676,0.00009728409,0.0001167037,0.00001608509,0.00190202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.459697,"threshold_uncertainty_score":0.6105302,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03058466263710136,"score_gpt":0.3733058540782329,"score_spread":0.3427211914411315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}