{"id":"W4414479811","doi":"10.1016/j.bbalip.2025.159691","title":"The B-lymphoblastoid model in Barth syndrome","year":2025,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Barth Syndrome Foundation","keywords":"Cardiolipin; Disease; Function (biology); Mechanism (biology); Penetrance; Mitochondrion; Mitophagy; Mitochondrial DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009524208,0.0006755286,0.0005623547,0.001251399,0.0004054758,0.001250302,0.0008163312,0.001757987,0.001606033],"category_scores_gemma":[0.0005317658,0.0002988905,0.0007262944,0.0006564257,0.0008248625,0.001279659,0.0008329282,0.002403676,0.001456537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009268178,"about_ca_system_score_gemma":0.0006762033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001366011,"about_ca_topic_score_gemma":0.001113154,"domain_scores_codex":[0.9995204,0.0001896818,0.00005545962,0.00007317279,0.0001178054,0.0000435193],"domain_scores_gemma":[0.9997429,0.0001194619,0.00004349675,0.00002403482,0.00003384582,0.00003618412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001389082,0.000367598,0.002677527,0.01095683,0.0002609167,0.006785157,0.001488784,0.003068306,0.4259675,0.2715726,0.02673182,0.248734],"study_design_scores_gemma":[0.0001245415,0.001246792,0.001519191,0.001146603,0.0002996373,0.008436848,0.0003513203,0.001799723,0.05773906,0.03108824,0.8961276,0.0001203895],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03972417,0.8292465,0.07981501,0.008982672,0.003356309,0.0003609344,0.001401711,0.000723691,0.03638911],"genre_scores_gemma":[0.1736862,0.7407685,0.06010436,0.004306362,0.001331046,0.0008047366,0.002281324,0.0001618788,0.01655566],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001757987,"threshold_uncertainty_score":0.006724596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01062471871689867,"score_gpt":0.2686315439581051,"score_spread":0.2580068252412064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}