{"id":"W4414491894","doi":"10.1158/2326-6074.cimm25-b002","title":"Abstract B002: Meta-Analysis of Neoantigens: Insights from the Cancer Epitope Database and Analysis Resource (CEDAR)","year":2025,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Epitope; Human leukocyte antigen; Cancer; Gene; Colorectal cancer; Mutation; MHC class I; Major histocompatibility complex","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01962446,0.001670039,0.006359219,0.01460245,0.0005762068,0.003345162,0.002826426,0.001353284,0.004416596],"category_scores_gemma":[0.03443992,0.0007724981,0.01390297,0.009807756,0.0003510927,0.001036802,0.002216134,0.001237882,0.0006287268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001062958,"about_ca_system_score_gemma":0.001548187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005137407,"about_ca_topic_score_gemma":0.006224064,"domain_scores_codex":[0.9844368,0.008704976,0.001576365,0.003124554,0.001773541,0.0003837551],"domain_scores_gemma":[0.9495214,0.04148697,0.003724296,0.003157994,0.001263902,0.0008454616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.006528083,0.000236368,0.2856998,0.04628444,0.5429797,0.001024482,0.0002298165,0.02186233,0.006828488,0.001673001,0.02546905,0.06118466],"study_design_scores_gemma":[0.002547767,0.002152675,0.3272598,0.006147555,0.5242063,0.003292425,0.0004752316,0.05178197,0.005473765,0.007474741,0.06881893,0.0003687578],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"dataset","genre_gemma":"empirical","genre_scores_codex":[0.2634369,0.280777,0.0407254,0.003521423,0.0004354739,0.001051168,0.4035109,0.003202691,0.003338998],"genre_scores_gemma":[0.7947667,0.01622387,0.03664248,0.001214871,0.0002668796,0.001257148,0.1482463,0.0006840559,0.0006976056],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01962446,"threshold_uncertainty_score":0.1037853,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.17940600139161,"score_gpt":0.4524553601177391,"score_spread":0.2730493587261291,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}