{"id":"W4414530417","doi":"10.1007/978-981-95-0673-6_31","title":"Hydrocortisone in Septic Shock: The ADRENAL Trial","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"ASTER","funders":"","keywords":"Hydrocortisone; Septic shock; Adrenal insufficiency; Sepsis; Resuscitation; Placebo; Mechanical ventilation; Shock (circulatory)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008456708,0.000449336,0.0005408396,0.0005705478,0.0002232977,0.001056914,0.0005056481,0.001531884,0.009856374],"category_scores_gemma":[0.001084896,0.0001614891,0.0002915757,0.0004790876,0.0006022402,0.001197257,0.0005053903,0.003079762,0.002040622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000547178,"about_ca_system_score_gemma":0.0008480437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009089715,"about_ca_topic_score_gemma":0.002719516,"domain_scores_codex":[0.9998617,0.00006491182,0.000007632402,0.00001154368,0.00004101721,0.00001318931],"domain_scores_gemma":[0.9995689,0.0003557764,0.00001518814,0.00001310129,0.00001499896,0.00003209924],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.001645573,0.0002184297,0.0001181685,0.001053286,0.00004979826,0.000470488,0.00007714273,0.0005181892,0.00084662,0.0593149,0.2758896,0.6597978],"study_design_scores_gemma":[0.001031763,0.000399073,0.0005867736,0.001194654,0.00003310298,0.0009168614,0.00004399734,0.0002471724,0.0004622763,0.01802449,0.9770422,0.00001750217],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.002778646,0.8287495,0.001065584,0.02306965,0.01012536,0.00005450216,0.000264306,0.00007343881,0.133819],"genre_scores_gemma":[0.03885803,0.6387588,0.00343948,0.04795332,0.01604084,0.0002203867,0.0004170488,0.0001200565,0.2541921],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.009856374,"threshold_uncertainty_score":0.03297287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556351054770425,"score_gpt":0.2658857352299862,"score_spread":0.2503222246822819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}