{"id":"W4414543657","doi":"10.1007/s42991-025-00517-8","title":"Succinate-driven cardiac mitochondrial respiration aligns with whole-animal hypoxia-tolerance in African mole-rats","year":2025,"lang":"en","type":"article","venue":"Mammalian Biology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Rimouski; University of Manitoba; University of Ottawa","funders":"","keywords":"Mitochondrion; Oxidative stress; Reactive oxygen species; Respiration; Mitochondrial DNA; Oxidative phosphorylation; Cellular respiration; Mitochondrial ROS","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001329497,0.0002622203,0.0003028995,0.0005125766,0.0002830307,0.0003306375,0.0002482786,0.0002952542,0.001538946],"category_scores_gemma":[0.0002660453,0.0002336826,0.000184298,0.0001573029,0.0005129732,0.000370158,0.0004376061,0.0005568428,0.0002000667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002577379,"about_ca_system_score_gemma":0.0001557215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00136587,"about_ca_topic_score_gemma":0.002050061,"domain_scores_codex":[0.9998757,0.00001133384,0.000009216868,0.00004801405,0.00002062644,0.00003513198],"domain_scores_gemma":[0.9996252,0.00002436936,0.0001666519,0.00005008376,0.00002964064,0.0001039518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001596375,0.00004613674,0.007761193,0.0000323645,0.00002878714,0.0001265328,0.0001192635,0.00008507602,0.9869021,0.0003224199,0.00006339061,0.002916286],"study_design_scores_gemma":[0.00003568236,0.0009192515,0.39083,0.00001602405,0.00007583203,0.001052404,0.000697651,0.001607938,0.6022149,0.0004776743,0.002047081,0.00002556583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984007,0.000181728,0.0008476819,0.00006455404,0.00001167153,0.000003537062,0.0001527935,0.00002187739,0.0003153498],"genre_scores_gemma":[0.9979522,0.0001441692,0.0004477026,0.00003773355,0.000005803124,0.00001329782,0.0001644284,0.00002091881,0.001213625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538946,"threshold_uncertainty_score":0.005148232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01041623006172938,"score_gpt":0.2488081719433508,"score_spread":0.2383919418816214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}