{"id":"W4414546928","doi":"10.1007/978-981-95-0673-6_30","title":"Hydrocortisone in Septic Shock: The CORTICUS Trial","year":2025,"lang":"en","type":"book-chapter","venue":"","topic":"Adrenal Hormones and Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"ASTER","funders":"","keywords":"Hydrocortisone; Septic shock; Placebo; Shock (circulatory); Randomized controlled trial; Sepsis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008027931,0.0002530958,0.0005116787,0.000138685,0.0000376394,0.00001181969,0.0001104098,0.0002776131,0.002116516],"category_scores_gemma":[0.00004758505,0.0001501622,0.0002354127,0.00004863135,0.00008643479,0.00001730259,0.00007120887,0.0004625116,0.0001925853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000066771,"about_ca_system_score_gemma":0.0002287002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001236553,"about_ca_topic_score_gemma":0.0002886348,"domain_scores_codex":[0.9987868,0.000007485749,0.0004455703,0.0002802254,0.0002705906,0.000209338],"domain_scores_gemma":[0.9993021,0.0001036273,0.0000924819,0.0003916698,0.00003481867,0.00007532051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.06321887,0.0005605729,0.0002901106,0.0004552072,0.0009211276,0.0008318115,0.000357779,0.00001550296,0.00004263054,0.5756037,0.2158241,0.1418786],"study_design_scores_gemma":[0.1123505,0.00323325,0.0007752907,0.001317672,0.001689403,0.00007865221,0.0003008601,0.001154571,0.00001975872,0.03308272,0.8449399,0.001057483],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.0009477574,0.001503318,0.0000975312,0.0017432,0.0002354243,0.001394662,0.0000050408,0.00005067035,0.9940224],"genre_scores_gemma":[0.03151618,0.0004724037,0.00004042713,0.001531753,0.000229802,0.00003197412,0.00003964064,0.00003051268,0.9661073],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.6291158,"threshold_uncertainty_score":0.9987957,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01545733724516096,"score_gpt":0.2660156821548435,"score_spread":0.2505583449096825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}