{"id":"W4414557116","doi":"10.1038/s42003-025-08682-9","title":"Archaic adaptive introgression in modern human reproductive genes","year":2025,"lang":"en","type":"article","venue":"Communications Biology","topic":"Forensic and Genetic Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; The Scarborough Hospital; Princess Margaret Cancer Centre; Hospital for Sick Children; University of Toronto","funders":"Social Sciences and Humanities Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Alliance de recherche numérique du Canada","keywords":"Introgression; Allele; Gene; Haplotype; Gene pool; Phenotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003210418,0.0002047426,0.0002540723,0.0008661387,0.000273076,0.0003085504,0.0002011332,0.0003029442,0.002436217],"category_scores_gemma":[0.0006903612,0.0001044136,0.0003416152,0.0007005028,0.0005014794,0.0001846132,0.0004709128,0.0004815294,0.0001425819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001618059,"about_ca_system_score_gemma":0.0001146819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005781273,"about_ca_topic_score_gemma":0.001177205,"domain_scores_codex":[0.9997261,0.00004942111,0.00001993911,0.0001069304,0.00005871545,0.00003888582],"domain_scores_gemma":[0.9995943,0.0001508782,0.0001076971,0.000069106,0.00003625282,0.00004179018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001234608,0.0001016289,0.5531343,0.0002155795,0.0008928648,0.002619204,0.001653378,0.0006333938,0.3906663,0.002802272,0.0003130376,0.04573356],"study_design_scores_gemma":[0.00003831538,0.0001766317,0.9848209,0.00002491884,0.0001674133,0.003177465,0.000266869,0.0003417892,0.007700656,0.001125659,0.00213761,0.00002180496],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997549,0.0004715731,0.0008441035,0.000057782,0.000007728418,0.00000525192,0.0001652869,0.000009082113,0.0008901792],"genre_scores_gemma":[0.9983498,0.0002737016,0.0006336748,0.00006859338,0.00001447945,0.000005585259,0.0002194113,0.00000748708,0.0004272023],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002436217,"threshold_uncertainty_score":0.008149981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04082195307198327,"score_gpt":0.3892145352956367,"score_spread":0.3483925822236534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}