{"id":"W4414573016","doi":"10.1016/j.pt.2025.09.006","title":"Cryptosporidium passes the bile acid test to survive","year":2025,"lang":"en","type":"article","venue":"Trends in Parasitology","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds de recherche du Québec","keywords":"Cryptosporidium; Pathogenesis; Metabolite; Virulence; Deoxycholic acid; Virulence factor; Bile acid; Parasite hosting","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003693117,0.0006790985,0.0008168968,0.0008637132,0.0006229396,0.0009363657,0.0003987717,0.001251405,0.008457823],"category_scores_gemma":[0.001447603,0.0002840146,0.0007529843,0.000424634,0.0004793365,0.0006483025,0.0007151387,0.0009637797,0.004736747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003622181,"about_ca_system_score_gemma":0.0006447607,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005285589,"about_ca_topic_score_gemma":0.007047807,"domain_scores_codex":[0.9988452,0.0001108084,0.00005682114,0.0001009418,0.0005789961,0.0003071086],"domain_scores_gemma":[0.9990362,0.0001397537,0.0001479916,0.00008320268,0.0003485475,0.0002442305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002188106,0.00060843,0.1836466,0.0004724719,0.0001960435,0.008507695,0.0009336522,0.0001831015,0.715782,0.00126394,0.009298514,0.07691918],"study_design_scores_gemma":[0.0001513504,0.006412775,0.2793335,0.0002348135,0.0002738933,0.02405076,0.00347338,0.001411246,0.6296015,0.001545889,0.05341211,0.00009877447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9364598,0.002008692,0.004582415,0.003053743,0.0007639769,0.0002148944,0.001075699,0.0005858966,0.05125473],"genre_scores_gemma":[0.9513211,0.001059065,0.005618117,0.001061976,0.0001178351,0.00003660938,0.0009862053,0.0001211788,0.03967795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008457823,"threshold_uncertainty_score":0.02829421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094185326869032,"score_gpt":0.3322240107436475,"score_spread":0.3212821574749572,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}