{"id":"W4414579295","doi":"10.1016/j.jaccas.2025.105226","title":"Cardiogenic Shock Patient Found to Have Cardiac Amyloidosis and Concurrent Multiple Myeloma","year":2025,"lang":"en","type":"article","venue":"JACC Case Reports","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Cardiogenic shock; Cardiac amyloidosis; Heart failure; Multiple myeloma; Amyloidosis; Etiology; Differential diagnosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001710049,0.0003504293,0.0004542623,0.0001170977,0.0001805465,0.00006814991,0.00005734636,0.0001929548,0.00001104481],"category_scores_gemma":[0.0003125981,0.0003359893,0.0003346344,0.0001416318,0.00006774089,0.000007058138,0.0003688116,0.00008740789,0.000007070534],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001250565,"about_ca_system_score_gemma":0.0001251253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003843631,"about_ca_topic_score_gemma":0.0002961897,"domain_scores_codex":[0.9978947,0.00008837252,0.0005287477,0.0008854141,0.0001998947,0.0004028519],"domain_scores_gemma":[0.9985323,0.00006642125,0.0001761813,0.0008326828,0.0001404048,0.0002520248],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000672399,0.0002110829,0.8887019,0.0000636323,0.00121649,0.01035777,0.0002279527,0.00008068344,0.02347332,0.00001725956,0.01540283,0.06017988],"study_design_scores_gemma":[0.001759663,0.0008394669,0.1831028,0.000139843,0.001038298,0.01262545,0.001508186,0.00004062751,0.397226,0.00004042795,0.400299,0.001380266],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917459,0.005173364,0.000140978,0.0002240676,0.0009214964,0.0009290654,0.00009699906,0.00003639408,0.0007317471],"genre_scores_gemma":[0.9975846,0.0003879173,0.0002699028,0.0004852096,0.0001226939,0.0004746778,0.0001195738,0.00003586405,0.0005195116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7055991,"threshold_uncertainty_score":0.9999092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00847665634226452,"score_gpt":0.266263956613799,"score_spread":0.2577873002715345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}