{"id":"W4414652833","doi":"10.3390/ijms26199566","title":"Developing Up-Scale Allogeneic Chondrocyte Therapies Using Juvenile Donor Cartilage","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council Canada; National Institute for Health and Care Research","keywords":"Chondrogenesis; Chondrocyte; Cartilage; Bioreactor; Autologous chondrocyte implantation; Regeneration (biology); Tissue engineering; Transplantation","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006184682,0.0004309527,0.0004192231,0.0003929392,0.0002017134,0.0006165325,0.0005096863,0.0004861164,0.002378698],"category_scores_gemma":[0.0003278786,0.0001534002,0.0004559813,0.0002234421,0.0002573367,0.0003267714,0.0005559028,0.000583353,0.001076725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002104285,"about_ca_system_score_gemma":0.0003440072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003641204,"about_ca_topic_score_gemma":0.001110379,"domain_scores_codex":[0.9995525,0.00005688959,0.00005517936,0.00007520219,0.00022191,0.00003824401],"domain_scores_gemma":[0.9995801,0.00005648322,0.0001238212,0.00006883004,0.00009261342,0.00007822795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002744171,0.00004835394,0.0002487926,0.00008600462,0.000005412263,0.00007063882,0.00001711495,0.00008981014,0.9945554,0.00006832434,0.00005394179,0.004728836],"study_design_scores_gemma":[0.00003475516,0.002329194,0.008832797,0.00008625397,0.00009013977,0.00133825,0.0001300313,0.001352284,0.9668172,0.0001749495,0.01879533,0.00001882815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8587452,0.009897659,0.1218242,0.0001912155,0.0002791029,0.001052155,0.0007603595,0.0004120243,0.006838222],"genre_scores_gemma":[0.8751873,0.008920019,0.1033624,0.000239065,0.00008053303,0.0005904384,0.002290088,0.0001451394,0.009184899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002378698,"threshold_uncertainty_score":0.007957578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02561138510668805,"score_gpt":0.3219410604512045,"score_spread":0.2963296753445165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}