{"id":"W4414657651","doi":"10.1084/jem.20250431","title":"CD2 and its ligands are involved in development and activation of MAIT cells","year":2025,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Cole Foundation; National Institutes of Health; Canadian Institutes of Health Research; Institut de Recherche Clinique De Montréal; Canada Research Chairs","keywords":"T-cell receptor; T cell; Cell; Signal transduction; Cell growth; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000157865,0.0003819282,0.0002514225,0.000243334,0.0001991252,0.000545214,0.0001598942,0.0004394588,0.002857708],"category_scores_gemma":[0.0002433029,0.0001212588,0.0002109452,0.0001182302,0.0002165707,0.0003652067,0.0004189169,0.000619644,0.0005793218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000169154,"about_ca_system_score_gemma":0.0001404291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001448874,"about_ca_topic_score_gemma":0.000111688,"domain_scores_codex":[0.999742,0.00006802527,0.00001665159,0.00005633956,0.00003432286,0.00008265978],"domain_scores_gemma":[0.9998555,0.00002213313,0.00003694173,0.00001615081,0.00001525146,0.0000539507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005724385,0.00003363033,0.002801658,0.0001241354,0.000008948519,0.0006136606,0.00006511152,0.00005543858,0.9896428,0.0005744855,0.0001607305,0.005347091],"study_design_scores_gemma":[0.0001201311,0.001103241,0.06926961,0.000100196,0.00008803435,0.00955377,0.0004908947,0.002095367,0.8732504,0.001352353,0.04254316,0.00003275557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800411,0.01189062,0.002890871,0.0002542435,0.00007627415,0.00003211704,0.0002173321,0.00008550213,0.00451198],"genre_scores_gemma":[0.9947292,0.001403713,0.001059353,0.00007427488,0.00005142831,0.00002387898,0.0001914093,0.0000141906,0.002452454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002857708,"threshold_uncertainty_score":0.009559989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01652493752930213,"score_gpt":0.2660121357768856,"score_spread":0.2494871982475835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}