{"id":"W4414672190","doi":"10.1101/2025.09.29.678806","title":"Lifespan Trajectories of Asymmetry in White Matter Tracts","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Advanced Neuroimaging Techniques and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Euroimmun Medizinische Labordiagnostika; Common Fund; National Institute of General Medical Sciences; National Institute on Deafness and Other Communication Disorders; National Institute of Mental Health; National Institute on Aging; Biotechnology and Biological Sciences Research Council; Avid Radiopharmaceuticals; University of Cambridge; University of Calgary; IXICO; Servier; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Canadian Institutes of Health Research; University of Queensland; Northern California Institute for Research and Education; Vanderbilt Institute for Clinical and Translational Research; National Institute on Drug Abuse; University of Pennsylvania; Vanderbilt University; Pfizer; BioClinica; Biogen; Illinois Department of Public Health; National Center for Advancing Translational Sciences; Cure Alzheimer's Fund; Alzheimer's Association; National Institutes of Health; U.S. Department of Health and Human Services; National Health and Medical Research Council; Foundation for the National Institutes of Health","keywords":"White matter; Asymmetry; Lateralization of brain function; Brain asymmetry; Neuroimaging; Scope (computer science); Association (psychology)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009033646,0.0002296897,0.0001733632,0.001190712,0.0002437571,0.000420927,0.0001508276,0.0001829944,0.001240799],"category_scores_gemma":[0.003198019,0.0001271599,0.0002555397,0.0006950301,0.000166253,0.0004149776,0.0006103672,0.0002761089,0.000269014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002330487,"about_ca_system_score_gemma":0.0002845771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004569938,"about_ca_topic_score_gemma":0.009823541,"domain_scores_codex":[0.9998503,0.00002865422,0.00001276142,0.00007313106,0.00001762527,0.00001747118],"domain_scores_gemma":[0.9990748,0.0002077823,0.0002606681,0.0001503538,0.0002150324,0.00009134781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003882017,0.00003134543,0.9175653,0.0001247753,0.0003158738,0.0005588964,0.001309408,0.003826221,0.01314743,0.002298961,0.004350451,0.05608311],"study_design_scores_gemma":[0.000007482805,0.00008057573,0.9855931,0.00007093383,0.00009456027,0.0007732928,0.0003325239,0.003047157,0.00190473,0.002340156,0.005732988,0.00002243402],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850371,0.0007469151,0.002929724,0.0000884431,0.000007094924,0.000009593528,0.01023617,0.00006556994,0.0008794291],"genre_scores_gemma":[0.9847177,0.000418678,0.003832026,0.00002929419,0.000005086243,0.00002904458,0.01031056,0.00003057328,0.0006270421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004569938,"threshold_uncertainty_score":0.009086668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02778107000388465,"score_gpt":0.2909587065365379,"score_spread":0.2631776365326533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}