{"id":"W4414688729","doi":"10.3390/ijms26199611","title":"Molecular Adaptations to Repeated Radiation Exposure in Triple-Negative Breast Cancer: Dysregulation of Cell Adhesion, Mitochondrial Function, and Epithelial–Mesenchymal Transition","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences North; NOSM University; Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Northern Ontario Heritage Fund Corporation; U.S. Department of Veterans Affairs","keywords":"Downregulation and upregulation; Extracellular matrix; Mitochondrion; Cell; Epithelial–mesenchymal transition; Integrin; Laminin; Cell adhesion; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187675,0.0002412197,0.000279682,0.0002677354,0.0001668493,0.0003051048,0.00009342143,0.0002297484,0.0008217711],"category_scores_gemma":[0.0001032316,0.0001158941,0.0002397392,0.0001956954,0.0001373942,0.0001332316,0.000162274,0.000348839,0.0001389038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002113511,"about_ca_system_score_gemma":0.0001745597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006779756,"about_ca_topic_score_gemma":0.001483748,"domain_scores_codex":[0.9998797,0.00002019761,0.000008914541,0.00002036123,0.0000423681,0.00002842141],"domain_scores_gemma":[0.9999479,0.000006310197,0.00002073008,0.000005840589,0.000008441175,0.00001077301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004518959,0.00001148243,0.0009093532,0.00003159927,0.000006256425,0.00005635021,0.00001771521,0.00004212048,0.9976003,0.00002124159,0.00002156711,0.001236823],"study_design_scores_gemma":[0.00001252378,0.0009560336,0.1891362,0.00002363508,0.00008632585,0.002074296,0.0003366756,0.001054065,0.8018464,0.000109655,0.004347441,0.00001666309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99514,0.002818654,0.001090103,0.00007781602,0.00001348346,0.00002258388,0.0002377714,0.00002959755,0.0005700726],"genre_scores_gemma":[0.9961228,0.001588796,0.0007794902,0.0000521834,0.00000610564,0.00002857,0.0004217169,0.000007052175,0.0009932705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008217711,"threshold_uncertainty_score":0.002749085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008467325724508446,"score_gpt":0.2748893430078385,"score_spread":0.2664220172833301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}