{"id":"W4414735770","doi":"10.1182/bloodadvances.2024015610","title":"Applying principles of vaccine development to oncomicrobial vaccines","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; Canada's Michael Smith Genome Sciences Centre; University of British Columbia; Spinal Cord Injury BC","funders":"Canadian Glycomics Network; Canadian Institutes of Health Research; Cancer Research UK","keywords":"Vaccination; Cervical cancer; Hepatitis B virus; Human papillomavirus; Cancer; Hepatitis B; Global health; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001065309,0.0001307079,0.0001785855,0.00006842164,0.00006876412,0.00001393372,0.0002245883,0.00005013021,0.000005572161],"category_scores_gemma":[0.00005191466,0.0001125259,0.00004717353,0.0001351579,0.000006206777,0.000006932864,0.0002151119,0.00003620816,0.000004245601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005365152,"about_ca_system_score_gemma":0.00008080263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003049976,"about_ca_topic_score_gemma":0.00003195255,"domain_scores_codex":[0.9992415,0.000009027672,0.0003542581,0.0001726727,0.00005859132,0.0001639173],"domain_scores_gemma":[0.9995646,0.00000674714,0.00009565465,0.0002316378,0.0000696674,0.00003170958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002228619,0.0002757125,0.02520359,0.000393783,0.0002243196,7.25182e-7,0.0001861796,0.001159125,0.8975463,0.001178965,0.0008881027,0.07272035],"study_design_scores_gemma":[0.0005815133,0.0000741387,0.00412692,0.00005324563,0.00001926106,0.000003624729,0.0001138737,0.00001147074,0.6276137,0.00001871503,0.3672692,0.0001143316],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863006,0.003771728,0.003937759,0.0001133638,0.0002034433,0.0004939096,0.000007477403,0.00001419227,0.005157458],"genre_scores_gemma":[0.9428224,0.0003138692,0.05428545,0.0003181703,0.00009549835,0.0001811774,0.00007084096,0.0000149636,0.001897651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3663811,"threshold_uncertainty_score":0.4588673,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010547017299021,"score_gpt":0.2487536718825591,"score_spread":0.2386482017095689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}