{"id":"W4414789265","doi":"10.1177/10668969251379897","title":"<i>TFEB</i> -Amplified Renal Cell Carcinoma: Integrating Histopathologic and Molecular Diagnostics with Therapeutic Implications","year":2025,"lang":"en","type":"article","venue":"International Journal of Surgical Pathology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Renal cell carcinoma; Nephrectomy; Eosinophilic; Kidney; PAX8; Immunohistochemistry; Clear cell; Histology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008391068,0.0004920344,0.0003538155,0.00084697,0.0003572927,0.001461942,0.0004586241,0.001164025,0.0004177552],"category_scores_gemma":[0.0009645512,0.0002678633,0.0002589606,0.0003628719,0.0009146176,0.001305082,0.0006662406,0.0008001256,0.0003438973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005665157,"about_ca_system_score_gemma":0.0004580738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005375842,"about_ca_topic_score_gemma":0.0007799541,"domain_scores_codex":[0.9997216,0.00007478333,0.00003471114,0.00003954629,0.00006015379,0.00006921441],"domain_scores_gemma":[0.9996556,0.0001120955,0.00007790687,0.0000311806,0.00006295128,0.0000602048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003560523,0.0001631414,0.1304598,0.0007555565,0.00006848892,0.3836792,0.0006183318,0.002950962,0.173681,0.006780475,0.005401488,0.2950855],"study_design_scores_gemma":[0.00001976447,0.0002651219,0.02840679,0.0002428665,0.00008863836,0.8875613,0.0009336607,0.009331729,0.03661038,0.004572252,0.0319073,0.00006026365],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8146402,0.0777939,0.0691793,0.01507864,0.0006647295,0.0001758789,0.0001708742,0.001013593,0.02128286],"genre_scores_gemma":[0.9594572,0.01320936,0.02456402,0.0008620167,0.001067257,0.0000165839,0.00006983281,0.0000297855,0.0007238705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001461942,"threshold_uncertainty_score":0.004437685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01599051533973918,"score_gpt":0.2794654625830981,"score_spread":0.263474947243359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}