{"id":"W4414789875","doi":"10.1101/2025.10.02.25337151","title":"Repetitive Transcranial Magnetic Stimulation in Substance Use Disorders is Safe and Tolerable: A Systematic Review of 141 Clinical Trials Including 4,299 Participants","year":2025,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Transcranial magnetic stimulation; Adverse effect; Clinical trial; Tolerability; Neuromodulation; Deep transcranial magnetic stimulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01263509,0.001582536,0.01071893,0.008944309,0.0009193885,0.002659635,0.001965301,0.002079819,0.005148877],"category_scores_gemma":[0.04258846,0.001110923,0.009826045,0.009596854,0.001334152,0.002220203,0.001745356,0.001101418,0.0004384914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003113803,"about_ca_system_score_gemma":0.008693914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004364839,"about_ca_topic_score_gemma":0.01415124,"domain_scores_codex":[0.9849609,0.004352109,0.00746176,0.0008939414,0.002058667,0.0002726196],"domain_scores_gemma":[0.9605984,0.02759359,0.007999289,0.0006252929,0.002828024,0.0003554627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0004519953,0.00001483348,0.0004041219,0.9673755,0.01272338,0.00008409641,0.0001097215,0.00004871241,0.0001860604,0.0000934396,0.0005267979,0.01798137],"study_design_scores_gemma":[0.001210589,0.0005803562,0.004396397,0.7774596,0.2023066,0.0003935909,0.0002905118,0.00007370588,0.0004196852,0.0003381932,0.0124791,0.00005176132],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002192838,0.9952207,0.000251096,0.0002022026,0.00008847008,0.0009197266,0.0007322818,0.00001659014,0.0003760859],"genre_scores_gemma":[0.03884714,0.9560742,0.001307814,0.0009461668,0.0001014885,0.001874012,0.0006330359,0.00001933083,0.0001967235],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01263509,"threshold_uncertainty_score":0.06682152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2985177136950296,"score_gpt":0.4480833868943649,"score_spread":0.1495656731993353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}