{"id":"W4414824425","doi":"10.1016/j.euroneuro.2025.08.156","title":"51. REAL-WORLD CLINICAL AND ECONOMIC IMPACT OF PHARMACOGENETIC-SUPPORTED PRESCRIBING IN KIDS: RESULTS FROM A LARGE CANADIAN MIRROR IMAGE TRIAL","year":2025,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; University of Calgary","funders":"","keywords":"Mental health; Clinical trial; Dosing; Health care; MEDLINE; Genetic testing; Health professionals","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001475701,0.0003088559,0.0007453628,0.0004337195,0.00008745208,0.00002920953,0.0002562794,0.00007322014,0.0006523259],"category_scores_gemma":[0.0004296529,0.0002823582,0.0002345217,0.0003447467,0.0002814225,0.0001104887,0.000201394,0.0008134932,0.00006997726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001624721,"about_ca_system_score_gemma":0.000584321,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04019232,"about_ca_topic_score_gemma":0.01542149,"domain_scores_codex":[0.9954951,0.001589557,0.001367614,0.0007888078,0.0001062791,0.0006526618],"domain_scores_gemma":[0.9976814,0.001005118,0.000310786,0.0003349762,0.0000661556,0.0006015642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3295406,0.001665345,0.2863523,0.0001161486,0.002219929,0.004337397,0.0005905652,0.00001620245,0.2340857,0.00004565689,0.1214287,0.01960144],"study_design_scores_gemma":[0.116919,0.0007681304,0.7624847,0.00005065945,0.000489107,0.000009786163,0.00002572674,0.0009173521,0.0002434388,0.00001449911,0.1178665,0.0002112124],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397053,0.0003518599,0.000001277384,0.003026563,0.001803815,0.001057466,0.0004695124,0.00006398688,0.05352023],"genre_scores_gemma":[0.9910967,0.003583514,0.0001417481,0.004215688,0.0003859692,0.00001306677,0.00004423553,0.00006258857,0.0004564938],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4761323,"threshold_uncertainty_score":0.9999629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07386398317772337,"score_gpt":0.4474446546324406,"score_spread":0.3735806714547172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}