{"id":"W4414849531","doi":"10.1242/dmm.052376","title":"Truncated CD19 as a selection marker for the isolation of stem cell-derived β-cells","year":2025,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta Hospital; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Institute of Nutrition, Metabolism and Diabetes; Michael Smith Health Research BC; University of Alberta; BC Children's Hospital","keywords":"Cell sorting; Stem cell; Embryonic stem cell; Selection (genetic algorithm); Stem cell marker; Mesenchymal stem cell; Negative selection; Cell; Cell type","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001724286,0.0001361327,0.0002160245,0.000101436,0.0001132676,0.00001568121,0.0000603322,0.00006757394,0.000100379],"category_scores_gemma":[0.0000266202,0.00009907418,0.0001562736,0.0002325424,0.00002074541,0.00007377386,0.00001740957,0.00006228782,0.00001074375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005195529,"about_ca_system_score_gemma":0.0002247572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002369402,"about_ca_topic_score_gemma":7.923244e-7,"domain_scores_codex":[0.9991289,0.00004330236,0.0002381127,0.0002284439,0.0001918602,0.0001693542],"domain_scores_gemma":[0.9991894,0.0001608317,0.00009011548,0.0002308552,0.0002177893,0.0001109707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002583956,0.0003222216,0.0001273659,0.0003664199,0.0001874978,0.00000105575,0.0001798229,0.002680252,0.9721742,0.01793252,0.001338065,0.002106611],"study_design_scores_gemma":[0.001967388,0.0001454943,0.0005292006,0.00008634064,0.0006991737,3.809787e-7,0.0002393719,0.6304196,0.3491413,0.01650835,0.0001733333,0.00009005555],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3824773,0.0002916803,0.6143154,0.0003928234,0.0002408439,0.001018197,0.00003031446,0.00007765502,0.001155783],"genre_scores_gemma":[0.9912714,0.0000342384,0.001642596,0.0008754026,0.00002712152,0.0002204703,0.00005245126,0.00001808554,0.005858267],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6277393,"threshold_uncertainty_score":0.4040128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01448876299449648,"score_gpt":0.2442971953813331,"score_spread":0.2298084323868366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}