{"id":"W4414849918","doi":"10.62792/ut.amb.v10.i19-20.p3043","title":"GENE THERAPY FOR CANCER TREATMENT: CONTEMPORARY APPROACHES AND PRINCIPLES","year":2025,"lang":"en","type":"article","venue":"Acta Medica Balkanika","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Genetic enhancement; Clinical trial; Cancer; Cancer therapy; Cancer treatment; Targeted therapy; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002324725,0.0007412893,0.001074688,0.00190454,0.0007896168,0.00260355,0.00128739,0.002076074,0.002270639],"category_scores_gemma":[0.0008044546,0.0003571962,0.0006052029,0.001374036,0.004006096,0.00247553,0.001379155,0.004254813,0.001516314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001585705,"about_ca_system_score_gemma":0.001382524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000974613,"about_ca_topic_score_gemma":0.001057483,"domain_scores_codex":[0.999113,0.0002376363,0.00005805928,0.0001385491,0.0003895219,0.00006329404],"domain_scores_gemma":[0.9995136,0.0002044561,0.00004636163,0.00004873944,0.000133656,0.00005313816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001400333,0.0003220509,0.0005803781,0.007584045,0.00008878937,0.0004769227,0.0007173825,0.002301514,0.02245281,0.1622296,0.02551808,0.7775882],"study_design_scores_gemma":[0.00003098722,0.0003809387,0.0006395477,0.001673035,0.00004176233,0.001633195,0.0002420881,0.0008777007,0.005994425,0.06621879,0.9222025,0.00006487891],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001131654,0.9590394,0.01917044,0.008093188,0.0007271934,0.00006695116,0.00004272978,0.00007934686,0.01164901],"genre_scores_gemma":[0.01534327,0.9601307,0.01522004,0.003055787,0.001643547,0.000240229,0.00006181311,0.00003826613,0.004266351],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00260355,"threshold_uncertainty_score":0.01229447,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.074647941802135,"score_gpt":0.3330534705824447,"score_spread":0.2584055287803097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}