{"id":"W4414869610","doi":"10.1182/bloodadvances.2025017194","title":"Matched unrelated vs haploidentical donor hematopoietic cell transplantation using posttransplant cyclophosphamide","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Moonshot; National Institute of Allergy and Infectious Diseases; Office of Naval Research; U.S. Navy; Legend Biotech; Alexion Pharmaceuticals; bluebird bio; Pharmacyclics; Daiichi Sankyo Europe; Takeda Oncology; Astellas Pharma US; University of Texas MD Anderson Cancer Center; AstraZeneca; Genentech; Adaptive Biotechnologies; Health Resources and Services Administration; National Institutes of Health; Janssen Research and Development; MorphoSys; Seagen; CareDx; BeiGene; Swedish Orphan Biovitrum; Astellas Pharma; Kiadis Pharma; Medac; Jazz Pharmaceuticals; Omeros Corporation; Karyopharm Therapeutics; HistoGenetics; Eli Lilly and Company; U.S. Department of Defense; Moonshot Research and Development Program; Sanofi; CSL Behring; Bristol-Myers Squibb; Vertex Pharmaceuticals; Mallinckrodt Pharmaceuticals; Gateway for Cancer Research; Actinium Pharmaceuticals; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Incyte; Pfizer; Amgen; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences","keywords":"Cyclophosphamide; Proportional hazards model; Confidence interval; Transplantation; Hematopoietic cell; Acute leukemia; Hematopoietic stem cell transplantation; Graft-versus-host disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002022746,0.00034759,0.000597126,0.0002479753,0.0001616037,0.00004410827,0.0001522115,0.0002183179,0.0001139091],"category_scores_gemma":[0.00002152998,0.0003258885,0.0001780591,0.0005606926,0.000119466,0.00026134,0.00001062248,0.000290675,0.00005215088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000546929,"about_ca_system_score_gemma":0.0001860837,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008063277,"about_ca_topic_score_gemma":0.00002120744,"domain_scores_codex":[0.9977419,0.00007474703,0.0007403966,0.000535837,0.0004287518,0.0004783547],"domain_scores_gemma":[0.9989955,0.0002479738,0.0001274424,0.0003304178,0.0001184639,0.0001801571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003688524,0.002170454,0.212509,0.01937337,0.0007012053,0.002830137,0.00367494,0.001042521,0.7485734,0.00424326,0.00007677571,0.001116454],"study_design_scores_gemma":[0.009236496,0.0002807787,0.0376582,0.003424296,0.004114347,0.001527396,0.000529361,0.0006004142,0.9399793,0.001313456,0.0007324315,0.0006034889],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9642705,0.003577162,0.0247847,0.0004729816,0.0004335841,0.0008756348,0.00006183465,0.0002709346,0.005252691],"genre_scores_gemma":[0.9855929,0.002723296,0.01027114,0.0004043344,0.00005063327,0.00003693602,0.0002018837,0.00004609128,0.0006727817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.191406,"threshold_uncertainty_score":0.9999193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068376123034541,"score_gpt":0.2736229463043908,"score_spread":0.2629391850740453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}