{"id":"W4414869610","doi":"10.1182/bloodadvances.2025017194","title":"Matched unrelated vs haploidentical donor hematopoietic cell transplantation using posttransplant cyclophosphamide","year":2025,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Moonshot; National Institute of Allergy and Infectious Diseases; Office of Naval Research; U.S. Navy; Legend Biotech; Alexion Pharmaceuticals; bluebird bio; Pharmacyclics; Daiichi Sankyo Europe; Takeda Oncology; Astellas Pharma US; University of Texas MD Anderson Cancer Center; AstraZeneca; Genentech; Adaptive Biotechnologies; Health Resources and Services Administration; National Institutes of Health; Janssen Research and Development; MorphoSys; Seagen; CareDx; BeiGene; Swedish Orphan Biovitrum; Astellas Pharma; Kiadis Pharma; Medac; Jazz Pharmaceuticals; Omeros Corporation; Karyopharm Therapeutics; HistoGenetics; Eli Lilly and Company; U.S. Department of Defense; Moonshot Research and Development Program; Sanofi; CSL Behring; Bristol-Myers Squibb; Vertex Pharmaceuticals; Mallinckrodt Pharmaceuticals; Gateway for Cancer Research; Actinium Pharmaceuticals; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Incyte; Pfizer; Amgen; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences","keywords":"Cyclophosphamide; Proportional hazards model; Confidence interval; Transplantation; Hematopoietic cell; Acute leukemia; Hematopoietic stem cell transplantation; Graft-versus-host disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000820672,0.0001787999,0.0004071206,0.0001440641,0.0001010012,0.0004781452,0.0002471094,0.0002693482,0.002003042],"category_scores_gemma":[0.001054512,0.00007344229,0.0005959788,0.000218116,0.0001901794,0.0002336626,0.0001976317,0.0004915307,0.0001475983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003819467,"about_ca_system_score_gemma":0.0004742183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003470259,"about_ca_topic_score_gemma":0.0006831324,"domain_scores_codex":[0.9995756,0.00016696,0.00004134336,0.00008768198,0.00005425007,0.00007420736],"domain_scores_gemma":[0.999359,0.0002624631,0.0001803764,0.00005066325,0.00001781182,0.0001296776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5937593,0.00793711,0.1691871,0.001039374,0.003812389,0.0003492314,0.000205527,0.006897739,0.0215235,0.001254158,0.001932501,0.1921021],"study_design_scores_gemma":[0.03489605,0.2640131,0.6483158,0.0004191372,0.005160342,0.001480015,0.0002369092,0.01234137,0.02606211,0.001846708,0.005158321,0.00007015536],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981517,0.0009859133,0.0001867923,0.00003039282,0.00004370443,0.00004810845,0.0001182628,0.000006583592,0.0004284258],"genre_scores_gemma":[0.9994901,0.000155836,0.00007087878,0.00003946774,0.00001779561,0.00002390593,0.0001202569,9.235425e-7,0.00008080403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002003042,"threshold_uncertainty_score":0.006700873,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01068376123034541,"score_gpt":0.2736229463043908,"score_spread":0.2629391850740453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}