{"id":"W4414902753","doi":"10.1139/cjpp-2024-0383","title":"Finding a link between the TRPV4 ion channel and angiogenesis: a potential therapeutic target for vascular remodeling","year":2025,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"TRPV4; Angiogenesis; Agonist; Transient receptor potential channel; Antagonist; Therapeutic angiogenesis; Blood vessel; TRPC1; Voltage-dependent calcium channel","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002962934,0.0002590105,0.0004680897,0.000309185,0.000219762,0.0004808355,0.0003975542,0.0007686338,0.002784312],"category_scores_gemma":[0.0002735915,0.0001012502,0.0004659311,0.0001953334,0.0004749543,0.0007520355,0.0003918098,0.001348986,0.0003560068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003988988,"about_ca_system_score_gemma":0.0006048947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004531224,"about_ca_topic_score_gemma":0.0007491908,"domain_scores_codex":[0.9998796,0.00002657915,0.000006999491,0.00001855775,0.00002608085,0.00004206822],"domain_scores_gemma":[0.9998957,0.00001837486,0.0000320213,0.000006293054,0.00002300336,0.00002453366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001410842,0.0004744201,0.00286351,0.003364994,0.0001536412,0.001436318,0.0001493048,0.0005907898,0.8532387,0.008366521,0.005450082,0.1225008],"study_design_scores_gemma":[0.0007789658,0.01210978,0.03920363,0.00115983,0.00111286,0.01372539,0.001152327,0.006240764,0.6682194,0.02751594,0.2285849,0.0001961625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4703767,0.4258676,0.04391439,0.03155688,0.003369201,0.0003389542,0.0007317326,0.0007314243,0.02311316],"genre_scores_gemma":[0.8611059,0.1211802,0.006848897,0.003163547,0.0007479038,0.0001378575,0.0003259553,0.00002790838,0.006461876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002784312,"threshold_uncertainty_score":0.009314477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0349795637254724,"score_gpt":0.2928543836611712,"score_spread":0.2578748199356988,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}