{"id":"W4414905477","doi":"10.1002/inmd.70056","title":"Tumor cell‐derived vaccines: Advances, challenges, and future prospects","year":2025,"lang":"en","type":"article","venue":"Interdisciplinary medicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immunotherapy; Immune system; Tumor cells; Antigen; Cancer immunotherapy; Clinical trial; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326547,0.0002356014,0.0002463593,0.00008065143,0.0001046767,0.000007333011,0.0002523531,0.00009927707,0.00005129784],"category_scores_gemma":[0.00003986452,0.0001901294,0.00005177918,0.00008282162,0.0001446,0.000008431389,0.0006443511,0.0001452431,0.000005572522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001954116,"about_ca_system_score_gemma":0.0000470885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.961952e-7,"about_ca_topic_score_gemma":0.00001171102,"domain_scores_codex":[0.9987809,0.00005008451,0.0002680036,0.0005341068,0.000124364,0.0002425177],"domain_scores_gemma":[0.9991851,0.00001785991,0.00008366523,0.0005081407,0.00007211679,0.0001331389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007776915,0.0004032917,0.001009482,0.001128457,0.0001356681,0.0002173844,0.001028606,0.000003549436,0.9198758,0.001397657,0.0127811,0.06124131],"study_design_scores_gemma":[0.009055583,0.004096366,0.05342211,0.001744766,0.0004690097,0.0002766395,0.01509576,0.0002194981,0.5305901,0.01574416,0.3677891,0.001496952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.550364,0.3939458,0.0002472183,0.01098825,0.000928458,0.0004825938,0.000009476381,0.00005325793,0.04298105],"genre_scores_gemma":[0.9862028,0.009707866,0.0003326344,0.0004662117,0.001433619,0.00005272723,0.00006642611,0.00002692278,0.001710784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4358389,"threshold_uncertainty_score":0.7753252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006332805239333813,"score_gpt":0.2790947196759768,"score_spread":0.272761914436643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}