{"id":"W4414905477","doi":"10.1002/inmd.70056","title":"Tumor cell‐derived vaccines: Advances, challenges, and future prospects","year":2025,"lang":"en","type":"article","venue":"Interdisciplinary medicine","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immunotherapy; Immune system; Tumor cells; Antigen; Cancer immunotherapy; Clinical trial; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002172406,0.0004766565,0.000726048,0.0006764276,0.000269484,0.001668628,0.0005759213,0.001889858,0.003280115],"category_scores_gemma":[0.001233014,0.0001760918,0.0004451507,0.0006431123,0.0008140221,0.0027439,0.0008637724,0.002405956,0.001374846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006529786,"about_ca_system_score_gemma":0.001680444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003955247,"about_ca_topic_score_gemma":0.0007208762,"domain_scores_codex":[0.9996451,0.0001123744,0.00002982134,0.00004327845,0.00009700577,0.00007239197],"domain_scores_gemma":[0.9992402,0.000339123,0.00007218894,0.00002698729,0.0002030144,0.0001186318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003469077,0.0003016422,0.0007322155,0.008347212,0.00007231402,0.0005288523,0.0002137809,0.002008523,0.02276774,0.05120821,0.0429889,0.8704838],"study_design_scores_gemma":[0.00005247213,0.0008018893,0.00100778,0.003204463,0.00009641692,0.001262627,0.0004349043,0.001176861,0.00656711,0.0378733,0.9474667,0.00005527535],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001756844,0.9853393,0.002116553,0.007747311,0.0007831389,0.00001576004,0.00005202841,0.00002936005,0.002159806],"genre_scores_gemma":[0.01488771,0.9760084,0.003111841,0.002984539,0.001238286,0.00005048497,0.0001373804,0.000009743746,0.001571561],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003280115,"threshold_uncertainty_score":0.01148891,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006332805239333813,"score_gpt":0.2790947196759768,"score_spread":0.272761914436643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}