{"id":"W4414948707","doi":"10.30683/1929-2279.2025.14.19","title":"Increased KI67 Immunostaining is Associated with Breast Cancer Aggressiveness","year":2025,"lang":"en","type":"article","venue":"Journal of cancer research updates","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Immunostaining; Breast cancer; Immunohistochemistry; Breast carcinoma; Lymph node; Cancer; Biomarker; Carcinoma; Staining","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000327913,0.0001510661,0.0001640784,0.0006166203,0.0001392782,0.0003135498,0.0001171614,0.0001732987,0.001995448],"category_scores_gemma":[0.0006379727,0.0001483692,0.00009193023,0.0003437528,0.0002232158,0.0001430147,0.0001636698,0.0002599678,0.0002731776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002310742,"about_ca_system_score_gemma":0.0001187452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00064175,"about_ca_topic_score_gemma":0.001166885,"domain_scores_codex":[0.9998554,0.00002647256,0.0000136336,0.00002309771,0.00005672888,0.00002463973],"domain_scores_gemma":[0.9991964,0.0001978927,0.0003426752,0.00003130181,0.0001358799,0.00009586805],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.000659698,0.00009171529,0.7485065,0.0002387457,0.0001116442,0.0005029051,0.0001608185,0.0001119988,0.2282142,0.000171782,0.0005406563,0.02068933],"study_design_scores_gemma":[0.000008453733,0.000130351,0.9816296,0.00001506334,0.0000618271,0.00182471,0.0001011737,0.0002403769,0.01427312,0.0001496441,0.001560166,0.000005372505],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939804,0.00345239,0.0006621687,0.0001152646,0.00001213023,0.0000103932,0.00008234078,0.00002856189,0.001656349],"genre_scores_gemma":[0.9978129,0.00107188,0.0004380915,0.00002876977,0.00001411925,0.000005483475,0.0001105302,0.000004402669,0.0005139097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001995448,"threshold_uncertainty_score":0.006675422,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02018665801136029,"score_gpt":0.3724763289933392,"score_spread":0.3522896709819789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}