{"id":"W4414960442","doi":"10.1007/s40266-025-01252-y","title":"Sarcopenia and Cachexia in Older Patients with Cancer: Pathophysiology, Diagnosis, Impact on Outcomes, and Management Strategies","year":2025,"lang":"en","type":"review","venue":"Drugs & Aging","topic":"Nutrition and Health in Aging","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network; University of Saskatchewan","funders":"","keywords":"Sarcopenia; Cachexia; Wasting; Quality of life (healthcare); Cancer cachexia; Psychological intervention; Cancer; Geriatric oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001551684,0.0003892831,0.001396451,0.0004396815,0.00008251537,0.00004543022,0.00007014249,0.0001110886,0.00002942749],"category_scores_gemma":[0.000006955327,0.0002530921,0.00008437422,0.0002561828,0.00005600767,0.00006778604,0.00008793084,0.0004373177,0.000002592919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002518628,"about_ca_system_score_gemma":0.0001968719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005057268,"about_ca_topic_score_gemma":0.00005523727,"domain_scores_codex":[0.9985064,0.00009896793,0.0003980998,0.0004796869,0.0001696142,0.0003472443],"domain_scores_gemma":[0.999277,0.0001696092,0.0001619008,0.0002302152,0.00003019843,0.0001310555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00003416338,0.0001513188,0.07479805,0.06380077,0.000144296,0.00004812503,0.0003001475,6.747163e-7,1.265621e-8,0.0001352253,0.0007621746,0.859825],"study_design_scores_gemma":[0.005535103,0.0002177051,0.5275659,0.2186392,0.001064778,0.000004127985,0.0002681177,0.000003980565,1.574693e-7,0.0001354123,0.2459716,0.0005938871],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009589457,0.9869401,9.536489e-7,0.0004161602,0.0001131418,0.002004633,0.00007413136,0.00003650035,0.0008249229],"genre_scores_gemma":[0.004263801,0.9936645,0.0001242806,0.001043044,0.0000382803,0.0005395606,0.0001709078,0.00003241286,0.0001232211],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8592312,"threshold_uncertainty_score":0.9999921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0200781405725675,"score_gpt":0.3879997841583037,"score_spread":0.3679216435857362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}