{"id":"W4414971312","doi":"10.70322/fibrosis.2025.10010","title":"Is “CTGF” Still a Viable Anti-Fibrotic Target?","year":2025,"lang":"en","type":"article","venue":"Fibrosis","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Drug development; Diabetes mellitus; Drug; Diabetic nephropathy; Subject (documents)","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001203267,0.0001599703,0.0001707363,0.0001017143,0.0000904496,0.00005032845,0.0002757198,0.0001439168,0.00062196],"category_scores_gemma":[0.000192978,0.0001616188,0.0001136532,0.0002966523,0.00007147693,0.000005037066,0.0002788443,0.000108646,0.0001704042],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003045808,"about_ca_system_score_gemma":0.0001179444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009082752,"about_ca_topic_score_gemma":0.000008593755,"domain_scores_codex":[0.9987847,0.00005672882,0.0001571528,0.0004661899,0.0001566647,0.0003785535],"domain_scores_gemma":[0.9992256,0.00002836209,0.00003216192,0.000505446,0.0001228811,0.0000855148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000061237,0.00005901317,0.038667,0.00008334049,0.00009426217,0.000002212862,0.00004242827,0.00001374453,0.9243367,0.0001667731,0.03565747,0.0008158531],"study_design_scores_gemma":[0.0003346532,0.0001344703,0.03078565,0.00003330175,0.00001217697,0.00000158255,0.00002158431,0.00006754233,0.6828051,0.0002833317,0.2853649,0.0001557297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847146,0.001466843,0.003479886,0.00093018,0.0002214839,0.0004053429,0.0001156933,0.0000427516,0.00862322],"genre_scores_gemma":[0.9855785,0.00005284391,0.001168145,0.0003614747,0.00009373642,0.0000404694,0.00006541562,0.00002204232,0.01261737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2497075,"threshold_uncertainty_score":0.6810026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01374672042575012,"score_gpt":0.2958039140115761,"score_spread":0.282057193585826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}