{"id":"W4414976681","doi":"10.1038/s41571-025-01080-4","title":"Unresectable stage III non-small-cell lung cancer: state of the art and challenges","year":2025,"lang":"en","type":"review","venue":"Nature Reviews Clinical Oncology","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Chemoimmunotherapy; Durvalumab; Stage (stratigraphy); Radiation therapy; Chemoradiotherapy; Immunotherapy; Clinical trial; Lung cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.002261999,0.0005992746,0.007906237,0.0001147007,0.00006616881,0.000009089184,0.0004208527,0.001637736,0.0001166519],"category_scores_gemma":[0.0007571864,0.0003005975,0.001705425,0.000411393,0.0002140698,0.0000248102,0.0003911896,0.002958899,0.00001594687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000680684,"about_ca_system_score_gemma":0.003537995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003752864,"about_ca_topic_score_gemma":0.0006541722,"domain_scores_codex":[0.9947306,0.001226705,0.002451065,0.0009286358,0.0002527146,0.0004102994],"domain_scores_gemma":[0.9932169,0.003386433,0.001874076,0.001113757,0.000172585,0.0002361964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003782925,0.000564951,0.0003119545,0.1550855,0.0006586236,0.00002919522,0.00001805874,8.568829e-8,2.404495e-8,0.00005699297,0.02282807,0.8204087],"study_design_scores_gemma":[0.001822195,0.0006175462,0.0001989891,0.08063005,0.008032061,0.00001083254,0.000003012719,0.000001430389,0.000001068972,0.000008008795,0.9084785,0.0001962933],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000008223415,0.9779587,0.0000014145,0.003061262,0.001753343,0.005937541,0.0001214683,0.00001599701,0.01114199],"genre_scores_gemma":[0.000003796558,0.9851749,0.0002346658,0.00135803,0.0004296512,0.001186991,0.00004064733,0.00004349395,0.01152784],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8856505,"threshold_uncertainty_score":0.9999446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.105190947120612,"score_gpt":0.4839786265831698,"score_spread":0.3787876794625578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}