{"id":"W4414979279","doi":"10.1016/s2468-1253(25)00264-x","title":"Lessons learned from the BOSS trial","year":2025,"lang":"en","type":"letter","venue":"The Lancet. Gastroenterology & hepatology","topic":"Colorectal Cancer Screening and Detection","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University Medical Centre","funders":"","keywords":"","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03629521,0.001391481,0.003152681,0.001186374,0.002967323,0.009177407,0.003289474,0.05203978,0.01601972],"category_scores_gemma":[0.1102329,0.0008558921,0.002838353,0.001260421,0.005841154,0.00727543,0.003419893,0.04379109,0.007295215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006402774,"about_ca_system_score_gemma":0.009112298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008299644,"about_ca_topic_score_gemma":0.01427127,"domain_scores_codex":[0.9746708,0.01461036,0.00181896,0.001607991,0.005145642,0.002146193],"domain_scores_gemma":[0.8983757,0.07564355,0.004082616,0.002230372,0.006616345,0.01305137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006827758,0.00005538174,0.0004434819,0.0003113113,0.0001463143,0.0005987223,0.0001139958,0.0001718686,0.0001047532,0.007044874,0.9662194,0.02410706],"study_design_scores_gemma":[0.005287291,0.0004993695,0.002397478,0.003534476,0.0004585053,0.0008809831,0.0004630713,0.0007025686,0.0003075377,0.05372458,0.9315627,0.0001813821],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002746979,0.007395707,0.00008160274,0.9752601,0.01428078,0.000007370959,0.000129034,0.00001937675,0.002551303],"genre_scores_gemma":[0.004322615,0.002973048,0.0002093155,0.9390991,0.05111709,0.00004515904,0.00007035954,0.00003475187,0.002128618],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05203978,"threshold_uncertainty_score":0.1919497,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07243908513520586,"score_gpt":0.3226776269880292,"score_spread":0.2502385418528233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}