{"id":"W4414980364","doi":"10.1016/j.jtct.2025.10.007","title":"Acute Toxicities of Bone Marrow Donation in Unrelated Donors with Sickle Cell Trait: A Center for International Blood and Marrow Transplantation Research Analysis","year":2025,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Blood Services","funders":"Center for International Blood and Marrow Transplant Research; National Institute of Allergy and Infectious Diseases; National Cancer Institute; Health Resources and Services Administration; Office of Naval Research; National Heart, Lung, and Blood Institute; U.S. Public Health Service","keywords":"Donation; Univariate analysis; Bone marrow; Population; Transplantation; Logistic regression; Bone pain; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003241392,0.0001290886,0.0002650612,0.0007370978,0.00007350848,0.00002187189,0.00004159566,0.0001333652,0.00003507867],"category_scores_gemma":[0.000002759617,0.0001049914,0.00007122364,0.0005771327,0.0001147223,0.00009241454,0.0000021166,0.0001631734,2.091112e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001693023,"about_ca_system_score_gemma":0.00004704851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000112714,"about_ca_topic_score_gemma":0.0001843953,"domain_scores_codex":[0.9989645,0.00007570758,0.0003252318,0.0002434106,0.0002239478,0.0001671493],"domain_scores_gemma":[0.9995546,0.00009254892,0.00006278567,0.00007789453,0.0001656604,0.00004647414],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02634596,0.001694164,0.1101027,0.00214398,0.004478599,0.0002175353,0.02807696,0.0005955047,0.8079734,0.002618029,0.00005124184,0.01570187],"study_design_scores_gemma":[0.09095813,0.002557526,0.114037,0.001259757,0.005109007,0.0001381732,0.00726576,0.01073542,0.764872,0.001291709,0.001043462,0.0007320278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902538,0.00126026,0.005692012,0.0008845002,0.00004325483,0.0006219915,0.0001514422,0.00001762993,0.00107512],"genre_scores_gemma":[0.9779482,0.02001024,0.0004440568,0.0001044033,0.000008480868,0.00004236964,0.0009700065,0.00001176484,0.0004605033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06461217,"threshold_uncertainty_score":0.4281426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0118820846600669,"score_gpt":0.2743756106895043,"score_spread":0.2624935260294374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}