{"id":"W4415040602","doi":"10.3390/cancers17203279","title":"Artemis (DCLRE1C) Acts as a Target to Enhance Radiotherapy Response in Triple-Negative Breast Cancer","year":2025,"lang":"en","type":"article","venue":"Cancers","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; St Joseph's Health Care; Western University; St. Michael's Hospital; London Health Sciences Centre","funders":"","keywords":"Radiation therapy; Biomarker; Breast cancer; Complete response; Radiation sensitivity; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002142327,0.0003410176,0.0004016493,0.0002969681,0.000226443,0.0004344261,0.0002113281,0.0004314407,0.002007378],"category_scores_gemma":[0.0002696429,0.0001321278,0.0003334755,0.000220052,0.0002139993,0.0001706564,0.000218698,0.0005270567,0.0007853632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004175599,"about_ca_system_score_gemma":0.000223624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006541322,"about_ca_topic_score_gemma":0.001393028,"domain_scores_codex":[0.9998552,0.00001964341,0.00001465091,0.00003684461,0.00005382364,0.00001973967],"domain_scores_gemma":[0.9998398,0.00003769724,0.00004960854,0.00001804689,0.00002392244,0.00003087343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001885701,0.00001707523,0.0008428999,0.000166811,0.00001850175,0.0001212135,0.00002039579,0.0004080159,0.9920899,0.0001218879,0.000324262,0.005680702],"study_design_scores_gemma":[0.00003680322,0.0003760509,0.007072944,0.00003199218,0.0001195077,0.0008541351,0.0000493601,0.002362372,0.9751452,0.0001241269,0.01380975,0.00001773184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9655862,0.01070974,0.01217099,0.0007594498,0.0001661634,0.0001258927,0.004165899,0.001287478,0.005028248],"genre_scores_gemma":[0.9891015,0.002252063,0.003664191,0.0002404065,0.00001681208,0.00004563261,0.001879619,0.00008089549,0.002718932],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002007378,"threshold_uncertainty_score":0.006715298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0141986814853781,"score_gpt":0.3801622659597083,"score_spread":0.3659635844743302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}