{"id":"W4415082452","doi":"10.1016/j.euo.2025.08.003","title":"Intermediate-risk Non–muscle-invasive Bladder Cancer: Recommendations for Definitions, Risk Stratification, Management Strategies, and Clinical Trial Design from the International Bladder Cancer Group","year":2025,"lang":"en","type":"article","venue":"European Urology Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; North York General Hospital","funders":"","keywords":"Clinical trial; Bladder cancer; Research design; Clinical study design; MEDLINE; Clinical research; Standard of care","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001027658,0.0002689492,0.0004298683,0.0001269226,0.0003826072,0.00007740264,0.0003557289,0.0001803437,0.0005652801],"category_scores_gemma":[0.0003012334,0.0002086058,0.0001616743,0.0001460203,0.0004253689,0.0001160286,0.0001519145,0.0005543244,0.00003732299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001888848,"about_ca_system_score_gemma":0.0007869647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007206068,"about_ca_topic_score_gemma":0.002889432,"domain_scores_codex":[0.9967551,0.001259466,0.0008205315,0.0007178708,0.000128321,0.0003186997],"domain_scores_gemma":[0.9965395,0.002282926,0.000446218,0.0004271439,0.0001902698,0.000113995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.03799913,0.002591972,0.03472534,0.00003502261,0.01188036,0.000102029,0.001502449,0.0001259452,0.0001057374,0.00670712,0.3155899,0.588635],"study_design_scores_gemma":[0.09956678,0.007171948,0.4899868,0.00008742107,0.007967545,0.00001175843,0.002820601,0.000643964,0.00003222186,0.011793,0.379492,0.00042602],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5020314,0.00965118,0.1766068,0.1775358,0.03136511,0.01962344,0.007220352,0.0005852721,0.07538066],"genre_scores_gemma":[0.9163303,0.05336881,0.00786612,0.01575249,0.002430881,0.002257251,0.00112184,0.00008035651,0.0007919411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.588209,"threshold_uncertainty_score":0.8506696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09042560362667153,"score_gpt":0.3835013916649181,"score_spread":0.2930757880382466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}