{"id":"W4415113293","doi":"10.14309/crj.0000000000001847","title":"Refractory Immune Checkpoint Inhibitor Colitis Treated With Biologics, Janus Kinase Inhibition, Plasma Exchange, and Fecal Microbiota Transplantation","year":2025,"lang":"en","type":"article","venue":"ACG Case Reports Journal","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Dalhousie University","funders":"","keywords":"Refractory (planetary science); Enterocolitis; Adverse effect; Fecal bacteriotherapy; Immune dysregulation; Vedolizumab; Colorectal cancer; Immune system; Ulcerative colitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003662592,0.001040349,0.001352849,0.001353849,0.002127928,0.001128757,0.0006134912,0.002771081,0.001358265],"category_scores_gemma":[0.001908048,0.0004396411,0.001325941,0.001060536,0.0008198536,0.001317173,0.0007560801,0.002979607,0.0004076737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001156748,"about_ca_system_score_gemma":0.0009455286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001523654,"about_ca_topic_score_gemma":0.002781627,"domain_scores_codex":[0.9995384,0.00006692138,0.00006198815,0.0000960594,0.00008593145,0.0001507721],"domain_scores_gemma":[0.9987653,0.000313709,0.0002920634,0.00007086439,0.00005132722,0.0005066931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00007339861,0.00005001542,0.006517321,0.00004139467,0.00002102348,0.9895588,0.00008102772,0.0001123803,0.0008808009,0.0001314936,0.0003605591,0.002171686],"study_design_scores_gemma":[0.0000192515,0.0001176405,0.003978203,0.00002954711,0.00002189448,0.9941682,0.00007411359,0.0003198769,0.0003453787,0.0001052124,0.0008112182,0.000009536374],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9391608,0.02538288,0.005414611,0.01186364,0.000783437,0.000255163,0.000281693,0.0004115578,0.01644613],"genre_scores_gemma":[0.9912178,0.003077816,0.001024054,0.00236489,0.0009559152,0.000022629,0.0001373926,0.00002733872,0.001172189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002771081,"threshold_uncertainty_score":0.008392811,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01011342951682049,"score_gpt":0.2509224801929451,"score_spread":0.2408090506761246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}