{"id":"W4415132558","doi":"10.1002/hem3.70216","title":"European Myeloma Network Group Consensus Statement on the use of next‐generation sequencing for prognostic stratification of newly diagnosed multiple myeloma","year":2025,"lang":"en","type":"article","venue":"HemaSphere","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Janssen Pharmaceuticals; Kite Pharma; EUSA Pharma; Servier; Adaptive Biotechnologies; Regeneron Pharmaceuticals; BeiGene; European Commission; Sanofi; PharmaMar; Celgene; Bristol-Myers Squibb; AstraZeneca; Amgen; Ministero della Salute; Pfizer; GlaxoSmithKline","keywords":"Multiple myeloma; Risk stratification; Workflow; Genetic testing; DNA sequencing; Statement (logic); MEDLINE","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07582785,0.001150661,0.00198465,0.004216937,0.001559781,0.004337981,0.004263068,0.006379416,0.003445644],"category_scores_gemma":[0.05782649,0.0007307436,0.003049364,0.003341836,0.002082462,0.002451008,0.004160495,0.00776083,0.003380345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003989236,"about_ca_system_score_gemma":0.02108258,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01217418,"about_ca_topic_score_gemma":0.009766738,"domain_scores_codex":[0.9665218,0.01607302,0.004890725,0.001595699,0.009469081,0.001449731],"domain_scores_gemma":[0.936691,0.02176965,0.004330543,0.002352925,0.03201282,0.002842938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004142281,0.0001176502,0.004501428,0.005419298,0.0003414564,0.0004939305,0.0007408619,0.002144612,0.002097359,0.01459349,0.5344625,0.4346731],"study_design_scores_gemma":[0.0001060883,0.0001085155,0.003535113,0.009624308,0.0003096577,0.000681325,0.0003078419,0.0007973777,0.001877257,0.01078155,0.9717914,0.00007970929],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.006518208,0.300362,0.09628339,0.4677795,0.04689299,0.00244276,0.00627375,0.00155306,0.07189436],"genre_scores_gemma":[0.07149231,0.3051134,0.2613344,0.2760891,0.01840904,0.005609852,0.02009633,0.001254716,0.04060077],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.07582785,"threshold_uncertainty_score":0.4010208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1709221740466713,"score_gpt":0.3226412180158104,"score_spread":0.1517190439691391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}