{"id":"W4415154131","doi":"10.3390/cells14201594","title":"Crosstalk Between Inflammasome Signalling and Epithelial-Mesenchymal Transition in Cancer and Benign Disease: Mechanistic Insights, Context-Dependence, and Therapeutic Opportunities","year":2025,"lang":"en","type":"review","venue":"Cells","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Crosstalk; Inflammasome; Signalling; Signalling pathways; Metastasis; Signal transduction; Hedgehog signaling pathway; Mechanism (biology)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001516598,0.0003968565,0.000739896,0.0001645646,0.000125879,0.00008723484,0.0001203357,0.0003385549,0.00001132974],"category_scores_gemma":[0.00001390765,0.0003568135,0.0001092183,0.00008569292,0.0002019037,0.00001094061,0.00009593526,0.0002108533,7.994981e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001808319,"about_ca_system_score_gemma":0.0003586415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004315099,"about_ca_topic_score_gemma":0.00006025404,"domain_scores_codex":[0.9985583,0.0001342883,0.000423459,0.0005100032,0.0001046503,0.0002693345],"domain_scores_gemma":[0.9994459,0.000075373,0.0001383871,0.0001862701,0.00004468284,0.0001094323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006346031,0.00003130302,0.00005811136,0.01347608,0.0003224617,0.00004482121,0.0003892331,0.000004944352,0.004852258,0.0005248107,0.00001865707,0.9802139],"study_design_scores_gemma":[0.001892372,0.0003716883,0.0002473087,0.01329356,0.002151111,0.00001323643,0.0009157858,0.00004460396,0.004806546,0.001719445,0.9727021,0.001842239],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02373939,0.9750531,0.0001061015,0.00002685944,0.00008482038,0.0006117685,0.0002995306,0.000008469362,0.0000699079],"genre_scores_gemma":[0.06325006,0.9355152,0.000008953371,0.00008414526,0.00009310566,0.000105757,0.0003379962,0.00003194694,0.0005728269],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9783716,"threshold_uncertainty_score":0.9998884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03423276225451959,"score_gpt":0.287916104172176,"score_spread":0.2536833419176564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}