{"id":"W4415187717","doi":"10.3390/molecules30204047","title":"Design, Characterization, and Hematopoietic Efficacy of a Fluorinated Pyrazolopiperidine Inclusion Complex","year":2025,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lethbridge College","funders":"","keywords":"Haematopoiesis; In vivo; Solubility; Aqueous solution; In vitro; Dissolution; Drug","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005275512,0.00009699971,0.0001625926,0.00004883591,0.000156775,0.00001308969,0.000122853,0.00005525786,0.0001795966],"category_scores_gemma":[0.00005535312,0.00009191847,0.00002709775,0.0001521221,0.00007356422,0.00002003836,0.0002430586,0.00004385806,0.000003374826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001250441,"about_ca_system_score_gemma":0.00002457536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006339986,"about_ca_topic_score_gemma":3.472976e-7,"domain_scores_codex":[0.9994279,0.00001244626,0.0002091315,0.0001731631,0.00007832491,0.00009909486],"domain_scores_gemma":[0.9995337,0.00008995623,0.00007313065,0.0002160535,0.00005902339,0.00002819743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001876409,0.0001052186,0.0001285265,0.0001131225,0.00001570543,6.736605e-7,0.0001912816,0.000007027679,0.9893047,0.003438734,0.00005074546,0.006625556],"study_design_scores_gemma":[0.0003432579,0.000007419417,0.005044793,0.00009336292,0.00002392594,0.000002107403,0.00002691389,0.001567838,0.9881886,0.000485407,0.004128005,0.00008837487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9611997,0.0001424003,0.03634613,0.0007738672,0.000008999234,0.00009868117,0.00001367768,0.00005583944,0.001360707],"genre_scores_gemma":[0.9980572,0.0000538838,0.001326193,0.0000615812,0.00001039125,0.00002873751,0.00006195774,0.000009652141,0.00039036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03685754,"threshold_uncertainty_score":0.3748327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524765728820717,"score_gpt":0.2567282524393912,"score_spread":0.241480595151184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}