{"id":"W4415187717","doi":"10.3390/molecules30204047","title":"Design, Characterization, and Hematopoietic Efficacy of a Fluorinated Pyrazolopiperidine Inclusion Complex","year":2025,"lang":"en","type":"article","venue":"Molecules","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lethbridge College","funders":"","keywords":"Haematopoiesis; In vivo; Solubility; Aqueous solution; In vitro; Dissolution; Drug","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001501798,0.0001999357,0.0001667365,0.00008066423,0.00008602838,0.0002643787,0.000194277,0.0001827874,0.0003346702],"category_scores_gemma":[0.0002060991,0.00008768668,0.00006883058,0.0001053274,0.0001339539,0.0001714141,0.0001115546,0.0001693754,0.0001346943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002911332,"about_ca_system_score_gemma":0.0001694775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004086633,"about_ca_topic_score_gemma":0.000317978,"domain_scores_codex":[0.9998962,0.00001682825,0.000008305726,0.00002861522,0.0000340103,0.00001603607],"domain_scores_gemma":[0.9998926,0.0000193791,0.00003945638,0.00001037827,0.00002065899,0.00001751053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000521836,0.00001955616,0.0000658548,0.0000296061,0.000001914435,0.00002652232,0.00001357158,0.0001753593,0.9982509,0.00006457964,0.00001634103,0.001283514],"study_design_scores_gemma":[0.00001171039,0.0002002445,0.0005002793,0.00000113396,0.000005641132,0.00006702221,0.000004577189,0.0009997473,0.9970134,0.00000576193,0.001186965,0.000003463532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913074,0.0007333764,0.00677401,0.00005031598,0.000007418458,0.00006857239,0.00009255265,0.00005122007,0.0009150881],"genre_scores_gemma":[0.9954416,0.0002851148,0.003066507,0.00001626015,0.000003664698,0.00003608947,0.00009693737,0.00000939831,0.001044534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004086633,"threshold_uncertainty_score":0.002112389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524765728820717,"score_gpt":0.2567282524393912,"score_spread":0.241480595151184,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}