{"id":"W4415201325","doi":"10.1093/asj/sjaf204","title":"OnabotulinumtoxinA Treatment for Masseter Muscle Prominence: 6-Month Safety and Efficacy Results, Including Patient-Reported Outcomes, From a Phase 3, Randomized, Placebo-Controlled, Multiregional Trial","year":2025,"lang":"en","type":"article","venue":"Aesthetic Surgery Journal","topic":"Facial Rejuvenation and Surgery Techniques","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SKiN Health; Spinal Cord Injury BC; University of British Columbia","funders":"Allergan; Galderma; AbbVie; Language Literacy and Culture, University of Maryland, Baltimore County","keywords":"Masseter muscle; Clinical trial; Phase (matter); Electromyography; MEDLINE","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003347575,0.001063467,0.001854094,0.0003296973,0.0004024887,0.0007415893,0.0005174411,0.001359392,0.0035191],"category_scores_gemma":[0.0021349,0.0003371779,0.002102709,0.0003749934,0.0006454872,0.0006585634,0.0003111392,0.00168762,0.0003508928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004914023,"about_ca_system_score_gemma":0.0008252461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003702998,"about_ca_topic_score_gemma":0.001092543,"domain_scores_codex":[0.9991009,0.0004560072,0.0001036069,0.0001160379,0.0001384616,0.00008490942],"domain_scores_gemma":[0.998193,0.0004781767,0.000818566,0.0001252072,0.0001411797,0.0002440294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8847405,0.0139213,0.003825215,0.002281902,0.003826214,0.00008509479,0.0001380615,0.0004155406,0.01520211,0.00008247307,0.00118383,0.07429776],"study_design_scores_gemma":[0.7535999,0.2213603,0.01825595,0.0001532713,0.002554806,0.0001601653,0.00004369753,0.0003206148,0.002137098,0.0001032206,0.00128805,0.00002284024],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848629,0.008889795,0.0006198837,0.0003995833,0.0001427484,0.002789038,0.0009096077,0.00006278733,0.001323672],"genre_scores_gemma":[0.9862206,0.006473283,0.001433468,0.0006587433,0.0003940244,0.002766536,0.001017397,0.0000209955,0.001014962],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0035191,"threshold_uncertainty_score":0.01770389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0489011789009741,"score_gpt":0.3470892631931152,"score_spread":0.2981880842921411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}