{"id":"W4415209196","doi":"10.1161/circresaha.125.327050","title":"SCarP: Proteome Heterogeneity Characterization of Primary Mouse Cardiomyocytes","year":2025,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Bruker (Canada)","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Proteome; Primary (astronomy); Primary cell; Cell; Myocyte; Proteomics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004262438,0.00093117,0.000862812,0.0007769161,0.001354051,0.001750833,0.001263548,0.01035343,0.002481521],"category_scores_gemma":[0.00741046,0.000642312,0.0006470254,0.0004413882,0.001581413,0.001050708,0.0008898392,0.009814547,0.003370367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002141176,"about_ca_system_score_gemma":0.000739376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008458005,"about_ca_topic_score_gemma":0.001757601,"domain_scores_codex":[0.9979237,0.000530113,0.0002105448,0.0002905936,0.0008394063,0.0002056181],"domain_scores_gemma":[0.9949963,0.003263819,0.0002400665,0.0002560549,0.000776908,0.0004667673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001348089,0.0001937843,0.001187713,0.0003833547,0.0000876358,0.005083807,0.0001756408,0.00020278,0.05515684,0.004816756,0.8734879,0.05787561],"study_design_scores_gemma":[0.0006315568,0.0006561961,0.008131447,0.0001721989,0.0002085646,0.007480386,0.0002644976,0.003925247,0.07565984,0.01911723,0.8836138,0.0001390406],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.02073415,0.02368616,0.01610113,0.788035,0.1362424,0.0003906701,0.001019492,0.0008065121,0.01298458],"genre_scores_gemma":[0.09302025,0.01949462,0.01233292,0.6212126,0.1718408,0.001040906,0.001093485,0.0004672924,0.07949708],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01035343,"threshold_uncertainty_score":0.02254218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06128939017812548,"score_gpt":0.3482352971334444,"score_spread":0.286945906955319,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}